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Chromatin immunoprecipitation using anti-ETV1 a.k.a. ER81 (Abcam: ab81086) antibodies or input DNA in an OE33 cell line
ORGANISM(S): Homo sapiens 
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
Chromatin immuno-precipitation using SUMO2 (Life Technologies) antibody in MCF10A cell line, treated with epidermal growth factor for 30 minutes.
ORGANISM(S): Homo sapiens 
Chromatin immunoprecipitation using anti-FOXM1 (Santa Cruz Biotechnology: sc- 502X) antibodies in an OE33 cell line
ORGANISM(S): Homo sapiens 
To determine genes regulated by the transcriptional co-activator PPARGC1A in OAC cells and whether PPARGC1A activity is altered by lapatinib we performed RNA-seq on OE19 cells treated with non-targeting siRNA or siRNA targeting PPARGC1A. 24 hours post-transfection, cells were also treated with eithe...
ORGANISM(S): Homo sapiens 
To investigate changes to gene expression associated with resistance to lapatinib, we performed ATAC-seq on OE19 cells treated with 500 nM lapatinib for 1, 7 and 35 days and vehicle control (DMSO) for 1 day.
ORGANISM(S): Homo sapiens 
Expression profiling was done of FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line (which stably expresses FOXK2).
ORGANISM(S): Homo sapiens 
Expression profiling was done of exposure to phorbol myristate acetate -PMA and FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line which stably expresses FOXK2. PMA is an inducer of AP1 activity.
ORGANISM(S): Homo sapiens 
There are nearly fifty forkhead (FOX) transcription factors encoded in the human genome and due to sharing a common DNA binding domain, they are all thought to bind to similar DNA sequences. It is therefore unclear how these transcription factors are targeted to specific chromatin regions to elicit ...
ORGANISM(S): Homo sapiens 
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