Sort   by:  
 Page size 
GenomicsAcetylation of histone H4 at lysine 44 facilitates meiotic recombination by creating accessible chromatin [ChIP-seq]
Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure directly regulate meiotic recombination. Here, we identify acetylation of histone H4 at Lys44 (H4K44ac) as a n...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-07 | E-GEOD-59003 | biostudies-arrayexpress
GenomicsBRD4 dynamics reveal novel acrosome-dependent chromatin reorganization during post-meiotic mammalian sperm development
During the post-meiotic phase of spermatogenesis, transcription is progressively repressed as the nuclei of haploid spermatids are compacted through a dramatic chromatin reorganization involving hyper-acetylation and replacement of most histones with sperm-specific protamines. Although BRDT has been...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-56526 | biostudies-arrayexpress
GenomicsAcetylation of histone H4 at lysine 44 facilitates meiotic recombination by creating accessible chromatin [Mnase-seq]
Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure directly regulate meiotic recombination. Here, we identify acetylation of histone H4 at Lys44 (H4K44ac) as a n...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-07 | E-GEOD-59004 | biostudies-arrayexpress
UnknownLong-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial.
Not available
S-EPMC3596060 | biostudies-literature
Sort   by:  
 Page size