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TranscriptomicsIdentification of pathogenic microRNAs in Helicobacter pylori-associated gastric cancer
To identify dysregulated miRNA(s) upon infection with H. pylori during different pre-malignant and malignant stages of gastric cancer in a mouse model miRNA expression in pre-neoplastic and neoplastic lesions in murine stomachs induced by H. pylori and N-methyl-N-nitrosourea (MNU) after 12 months wa...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-62503 | biostudies-arrayexpress
ProteomicsIdentification of novel urine proteomic biomarkers for high stamina in high-altitude adaptation
Ascending to high-altitude of non-high-altitude natives showed rapidly declined physical ability, but some with high-altitude adaptability were still able to maintain a high level. Our goal was to find urine biomarkers that could be used to assess people for high-altitude hypoxia adaptation with hig...
ORGANISM(S): Human Parechovirus Strain T82-0169 
2023-02-02 | PXD039791 |
TranscriptomicsWhole blood-derived miRNA signatures in mice exposed to lipopolysaccharide
To profile the expression of microRNAs (miRNAs) in the whole blood of mice in exposure to intraperitoneal lipopolysaccharide (LPS) injection. C57BL/6 mice which received intraperitoneal injections of different concentration (ranged from 10 to 1000 μg) of LPS originated from different bacteria, incl...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-36472 | biostudies-arrayexpress
UnknownElevated Serum Interleukin-34 Level in Patients with Systemic Lupus Erythematosus Is Associated with Disease Activity.
Not available
S-EPMC5823931 | biostudies-literature
TranscriptomicsMicroarray analysis of the effect of hsa-miR-127-3p on the gene expression of Hela cells under the stimulation with IFN-α
In order to explore the effect of hsa-miR-127-3p on the gene expression downstream of type I interferon signaling pathway, we used IFN-α to treat Hela cells (1000U/ml for 8 h) which were previously transfected with hsa-miR-127-3p mimics or various controls (mock transfection, negative control mimics...
ORGANISM(S): Homo sapiens 
2021-10-08 | E-MTAB-10804 | biostudies-arrayexpress
TranscriptomicsmiRNAs expression in the splenic CD4+ T cells and B cells isolated from MRL/lpr mice at 5 and 16 weeks of age
To identify any differentially expressed miRNAs in the CD4+ T cells of lupus. MicroRNAs (miRNAs) have been implicated as fine-tuning regulators controlling diverse biological processes at the level of posttranscriptional repression. Dysregulation of miRNAs has been described in various disease stat...
ORGANISM(S): Mus musculus 
2010-07-06 | E-GEOD-21220 | biostudies-arrayexpress
TranscriptomicsApplied Biosystems Human TaqMan Low Density Array (TLDA) in HCC tumor and adjacent non-tumor tissues
MicroRNAs (miRNAs) are aberrant expressed in hepatocellular carcinoma (HCC) tissue and play a central role in diverse biological processes. We conducted a genome-wide miRNAs screening in 10 pairs of HCC tumor and adjacent non-tumor tissues to test the hypothesis that dysregulation of miRNAs in HCC t...
ORGANISM(S): Homo sapiens 
2014-02-08 | E-GEOD-54751 | biostudies-arrayexpress
TranscriptomicsGenome-Wide binding sites of two MADS-domain transcription factors SOC1 and SVP in Arabidopsis during the floral transition
The floral transition in Arabidopsis is tightly controlled by complex genetic regulatory networks in response to endogenous and environmental flowering signals. SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) and SHORT VEGETATIVE PHASE (SVP), two key MADS-domain transcription factors, perceive the...
ORGANISM(S): Arabidopsis thaliana 
2012-02-01 | E-GEOD-33297 | biostudies-arrayexpress
ProteomicsProteomic analysis of the invasiveness of human bladder cancer cells
To identification of key drivers involved in the development of muscle invasive bladder cancer, which displays poor prognosis, we isolated one subpopulation of human 5637 bladder cancer cells with highly invasiveness and the other subpopulation of 5637 cells with low invasiveness by Transwell method...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-27 | MSV000082854 | MassIVE
TranscriptomicsApplied Biosystems Human TaqMan Low Density Array (TLDA) in plasma samples from HCC cases and controls
MicroRNAs (miRNAs) are abundant in the circulation and play a central role in diverse biological processes; they may be useful for early diagnosis of hepatocellular carcinoma (HCC). We conducted a two-phase, case-control study (20 pairs for the discovery set and 49 pairs for the validation set) to t...
ORGANISM(S): Homo sapiens 
2013-08-21 | E-GEOD-50013 | biostudies-arrayexpress
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