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MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7711 | MetaboLights
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7713 | MetaboLights
TranscriptomicsGenome-wide analysis of microRNAs and their targets involving in leaf senescence of rice
Enhancing grain production of rice (Oryza sativa L.) is a top priority in ensuring food security for human being. One approach to increase yield is to delay leaf senescence and to extend the available time for photosynthesis. microRNAs (miRNAs) are key regulators for aging and cellular senescence in...
ORGANISM(S): Oryza sativa 
2015-01-01 | E-GEOD-62200 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownMultipart Chaperone-Effector Recognition in the Type III Secretion System of Chlamydia trachomatis.
Not available
S-EPMC4653673 | biostudies-literature
TranscriptomicsGenome-Wide binding sites of two MADS-domain transcription factors SOC1 and SVP in Arabidopsis during the floral transition
The floral transition in Arabidopsis is tightly controlled by complex genetic regulatory networks in response to endogenous and environmental flowering signals. SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) and SHORT VEGETATIVE PHASE (SVP), two key MADS-domain transcription factors, perceive the...
ORGANISM(S): Arabidopsis thaliana 
2012-02-01 | E-GEOD-33297 | biostudies-arrayexpress
UnknownJin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1α pathway.
Not available
S-EPMC10568827 | biostudies-literature
UnknownUHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson's disease mice after oral administration of Wen-Shen-Yang-Gan decoction.
Not available
S-EPMC8386550 | biostudies-literature
TranscriptomicsRNA-seq profiles of Arabidopsis thaliana wild-type and fip37-4 LEC1:FIP37
N6-methyladenosine (m6A) represents the most prevalent internal modification on messenger RNA, and requires a multicomponent m6A methyltransferase complex in mammals. How their plant counterparts determine the global m6A modification landscape and its molecular link to plant development remain elusi...
ORGANISM(S): Arabidopsis thaliana 
2016-07-25 | E-GEOD-75507 | biostudies-arrayexpress
UnknownCase study of 3D fingerprints applications.
Not available
S-EPMC5388323 | biostudies-literature
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