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TranscriptomicsX-inactivation in hESCs
X chromosome inactivation (XCI) is a dosage compensation mechanism in female cells to regulate X-linked gene expression. We report here that subcultures from established lines of female hESCs displayed variations (0-100%) in the expression of XCI markers such as XIST RNA coating and enrichment of h...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-9637 | biostudies-arrayexpress
TranscriptomicsExpression data from testes and abdomen in fertile and sterile introgression males
Postmating reproductive isolation is often manifested as hybrid male sterility, for which X-linked genes are over-represented. In contrast, X-linked gene are significantly under-represented among testis-expressing gene.This seeming contradiction may be germane to the X:autosome imbalance hypothesis ...
ORGANISM(S): Drosophila simulans 
2010-05-19 | E-GEOD-21734 | biostudies-arrayexpress
UnknownIdentification of the Active Constituents and Significant Pathways of Shen-qi-Yi-zhu Decoction on Antigastric Cancer: A Network Pharmacology Research and Experimental Validation.
Not available
S-EPMC8629626 | biostudies-literature
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownThe depletion of gut microbiome impairs the beneficial effect of Gui-Shen-Wan in restoring mice ovarian function and associated protein expression of ovarian tissues.
Not available
S-EPMC11632464 | biostudies-literature
ProteomicsProteomics analysis of the membrane vesicles in Pseudomonas aeruginosa under X-ray irradiation
Pseudomonas aeruginosa, X-ray irradiation, inner membrane blebbing, membrane vesicles Almost all bacteria produce membrane vesicles (MVs) that have been found to be generally composed of lipopolysaccharides (LPSs), phospholipids (PLs), outer membrane proteins, periplasmic proteins and peptidoglycan ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-08-25 | PXD037062 | Pride
X-ray irradiation Membrane vesicles Proteomics analysis Pseudomonas aeruginosa 
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
TranscriptomicsTop3M-NM-2 is an RNA topoisomerase that works with Fragile X syndrome protein to promote synapse formation
Topoisomerases are crucial to solve DNA topological problems, but they have not been linked to RNA metabolism. Here we show that human topoisomerase 3M-NM-2 (Top3M-NM-2) is an RNA topoisomerase that biochemically and genetically interacts with FMRP, a protein deficient in Fragile X syndrome and know...
ORGANISM(S): Homo sapiens 
2013-08-04 | E-GEOD-47502 | biostudies-arrayexpress
UnknownNetwork Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer's Disease.
Not available
S-EPMC7774966 | biostudies-literature
UnknownLiu Shen Capsule Alters Airway Microbiota Composition and Metabolite Profiles in Healthy Humans.
Not available
S-EPMC8831732 | biostudies-literature
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