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ModelsDeVries2000_PancreaticBetaCells_InsulinSecretion
This a model from the article: Channel sharing in pancreatic beta -cells revisited: enhancement of emergent bursting by noise. De Vries G, Sherman A. J Theor Biol2000 Dec 21;207(4):513-30 11093836, Abstract: Secretion of insulin by elect...
2024-09-02 | BIOMD0000000371 | BioModels
GenomicsA master cistromic circuit governing hepatic fibrogenesis [ChIP-seq]
Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanisms that govern this process remain unclear. Here, we reveal a novel cistromic circuit in HSCs compris...
ORGANISM(S): Homo sapiens 
2013-04-29 | E-GEOD-38103 | biostudies-arrayexpress
ModelsBertram2006_ATPproduction_Mitochondrial
This a model from the article: A simplified model for mitochondrial ATP production. Bertram R, Gram Pedersen M, Luciani DS, Sherman A. J Theor Biol 2006 Dec 21;243(4):575-86 16945388 , Abstract: Most of t...
2005-01-01 | MODEL1006230114 | BioModels
TranscriptomicsA Master Cistromic Circuit Governing Hepatic Fibrogenesis
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2013-04-29 | E-GEOD-41580 | biostudies-arrayexpress
ModelsBertram2004_PancreaticBetaCell_modelB
This a model from the article: Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Bertram R, Satin L, Zhang M, Smolen P, Sherman A. Biophys J2004 Nov;87(5):3074-87 15347584, Abstract: Pancreatic islets of Langer...
2024-09-02 | BIOMD0000000373 | BioModels
GenomicsSuper-Enhancer-mediated Control of Liver Fibrosis by BET Bromodomain Proteins
Here, we investigate the role of enhancers in myofibroblasts, a cell type that dominates the pathogenesis and progression of tissue fibrosis. We reveal that bromodomain and extra-terminal family members (BETs), an important group of epigenetic readers, are critical for super-enhancer-mediated pro-fi...
ORGANISM(S): Homo sapiens 
2015-12-11 | E-GEOD-58680 | biostudies-arrayexpress
ModelsBertram2004_PancreaticBetaCell_modelA
This a model from the article: Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Bertram R, Satin L, Zhang M, Smolen P, Sherman A. Biophys J 2004 Nov;87(5):3074-87 15347584 , Abstract: ...
2005-01-01 | MODEL1006230071 | BioModels
UnknownUnderstanding racial-ethnic differences in patient-centered care (PCC) in oncology through a critical race theory lens: A qualitative comparison of PCC among Black, Hispanic, and White cancer patients.
Not available
S-EPMC9117574 | biostudies-literature
ModelsBertram2007_IsletCell_Oscillations
This is the model described in the article: Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets. Bertram R, Satin LS, Pedersen MG, Luciani DS, Sherman A. Biophys J. 2007 Mar 1;92(5):1544-55. Pubmed ...
2024-09-02 | BIOMD0000000376 | BioModels
ModelsMears1997_CRAC_PancreaticBetaCells
This a model from the article: Evidence that calcium release-activated current mediates the biphasic electrical activity of mouse pancreatic beta-cells. Mears D, Sheppard NF Jr, Atwater I, Rojas E, Bertram R, Sherman A. J Membr Biol1997 Jan 1;155(1):47-59 90024...
2024-09-02 | BIOMD0000000375 | BioModels
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