Sort   by:  
 Page size 
MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
ProteomicsPterosin B treatment protect cells from glutamate-induced cytotoxicity
The prevalence of neurodegenerative diseases is rapidly increasing with the aging trend of global populations, severely threatening human health and burdening society. However, to date, there is no effective treatment able to halt the progression or cure the diseases. Here, We aim to develop effecti...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-01 | PXD030396 | Pride
Ros Neuroprotective natural products Glutamate excitotoxicity Mitochondria membrane potential 
UnknownLow G preconditioning reduces liver injury induced by high +Gz exposure in rats.
Not available
S-EPMC4458764 | biostudies-literature
TranscriptomicsIdentification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq
Many diseases and adverse drug reactions exhibit tissue specificity. To better understand the tissue-specific expression characteristics of transcripts in different human tissues, we deeply sequenced RNA samples from 14 different human tissues. After filtering many lowly expressed transcripts, 24,72...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-83115 | biostudies-arrayexpress
UnknownDevelopmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytes.
Not available
S-EPMC11741303 | biostudies-literature
MetabolomicsLipidomic Changes in the Liver of Beagle Dogs Associated with Toxocara canis Infection

In this study, lipid alterations in Beagle dog’s liver caused by Toxocara canis infection were investigated by using liquid chromatography with tandem mass spectrometry at 12 hours post infection (hpi), 24 hpi and 36 days post infection (dpi). A total of 6 categories and 42 subclasses of...

2022-08-30 | MTBLS4015 | MetaboLights
UnknownFine mapping of wheat stripe rust resistance gene Yr26 based on collinearity of wheat with Brachypodium distachyon and rice.
Not available
S-EPMC3589488 | biostudies-literature
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
UnknownMapping of major QTL and candidate gene analysis for hull colour in foxtail millet (Setaria italica (L.) P. Beauv.).
Not available
S-EPMC10428602 | biostudies-literature
TranscriptomicsAn Investigation of Biomarkers Derived from Legacy Microarray Data for Their Utility in the RNA-Seq Era
Gene expression microarray has been the primary biomarker platform ubiquitously applied in biomedical research, resulting in enormous data, predictive models and biomarkers accrued. Recently, RNA-seq has looked likely to replace microarrays, but there will be a period where both technologies coexist...
ORGANISM(S): Homo sapiens 
2014-10-22 | E-GEOD-62564 | biostudies-arrayexpress
Sort   by:  
 Page size