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In this experiment, we've examined chromatin conformation of OG2 (B6; CBA-Tg(Pou5f1-EGFP)2Mnn/J; stock number 004654) mouse stem cells cultured as described in (Shi et al., 2008), using different amounts of starting cells. We performed a modified in situ Hi-C protocol for 6 samples digested with Mbo...
ORGANISM(S): Mus musculus 
Human umbilical cord blood cells (UCB) is an important alternative resource for the hematopoietic stem cells in treatment of leukemia and other non-malignant diseases. The failure of hematopoiesis reconstruction by the UCB is known to be associated with several clinicopathological features of host p...
ORGANISM(S): Homo sapiens 
Mechanical stress is a measure of internal resistance exhibited by a body or material when external forces, such as compression, tension, bending, etc. are applied. The study of mechanical stress on health and aging is a continuously growing field, as major changes to the extracellular matrix and ce...
ORGANISM(S): Caenorhabditis elegans 
Here, we used PhastID to explore the proximal interactome of PD-L1 in human cancer cells to identify promising posttranslational regulators of PD-L1.Proximal proteomics showed that proteins interacting with C-terminal of PD-L1 were specifically enriched in protein degradation and immune system, whil...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD077446 | Pride

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS288 | MetaboLights
The detachment of epithelial cells, but not cancer cells, causes anoikis due to reduced energy production. Invasive tumor cells generate three splice variants of the metastasis gene osteopontin. The cancer-specific form osteopontin-c supports anchorage-independence through inducing oxidoreductases a...
ORGANISM(S): Homo sapiens 
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