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TranscriptomicsA systematic evaluation of miRNA: mRNA interactions involved in the migration and invasion of breast cancer cells [miRNA Array]
In this study we performed a systematic evaluation of functional miRNA-mRNA interactions associated with the aggressiveness of breast cancer cells using a combination of integrated miRNA and mRNA expression profiling, bioinformatics prediction, and functional assays. Analysis of the miRNA expression...
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-40056 | biostudies-arrayexpress
GenomicsTargeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing
We applied the solution hybrid selection approach to the enrichment of CpG islands (CGIs) and promoter sequences from the human genome for targeted high-throughput bisulfite sequencing. A single lane of Illumina sequences allowed accurate and quantitative analysis of 1 million CpGs in more than 21,4...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-26826 | biostudies-arrayexpress
GenomicsGenome-wide DNA methylation maps in chronic lymphocytic leukemia cells determined by next-generation sequencing
We conducted a genome-wide DNA methylation analysis in CD19+ B-cells from CLL patient and normal control samples using reduced representation bisulfite sequencing (RRBS). The methylation status of 1.8-2.3 million CpGs in the CLL genome was determined; about 45% of these CpGs were located in more tha...
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-32698 | biostudies-arrayexpress
TranscriptomicsA systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells [HG-U133_Plus_2]
In this study we performed a systematic evaluation of functional miRNA-mRNA interactions associated with the aggressiveness of breast cancer cells using a combination of integrated miRNA and mRNA expression profiling, bioinformatics prediction, and functional assays. Analysis of the miRNA expression...
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-40057 | biostudies-arrayexpress
TranscriptomicsA systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells [HuGene-1_0-st]
In this study we performed a systematic evaluation of functional miRNA-mRNA interactions associated with the aggressiveness of breast cancer cells using a combination of integrated miRNA and mRNA expression profiling, bioinformatics prediction, and functional assays. Analysis of the miRNA expression...
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-40058 | biostudies-arrayexpress
UnknownTaxonomic study on the subgenus Orientostichus, the Pterostichuspulcher species group (Coleoptera, Carabidae, Pterostichus).
Not available
S-EPMC10448245 | biostudies-literature
TranscriptomicsA systematic evaluation of miRNA: mRNA interactions involved in the migration and invasion of breast cancer cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-40059 | biostudies-arrayexpress
GenomicsAn inherently bi-functional subset of Foxp3+ Treg/T-helper cells is controlled by the transcription factor Eos
At sites of inflammation, certain Foxp3+ Tregs have the ability to alter their phenotype and become pro-inflammatory helper/effector cells, without losing Foxp3 expression. We show that this functional reprogramming is controlled by the transcription factor Eos (Ikzf4), an obligate co-repressor for...
ORGANISM(S): Mus musculus 
2013-02-20 | E-GEOD-44380 | biostudies-arrayexpress
TranscriptomicsLarge-scale characterization of DNA methylation changes in human gastric carcinomas with and without metastasis
A large-scale characterization of the methylation states of candidate CpG islands (CGIs) throughout the gastric cancer methylome has not previously been conducted. Genome-wide DNA methylation profiles were compared between 4 metastatic and 4 non-metastatic gastric carcinomas (GCs) and their surgical...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-47724 | biostudies-arrayexpress
UnknownUsing metabolic abnormalities of carriers in the neonatal period to evaluate the pathogenicity of variants of uncertain significance in methylmalonic acidemia.
Not available
S-EPMC11284102 | biostudies-literature
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