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TranscriptomicsMAQC-II Project: NIEHS data set
The NIEHS data set (endpoint C) was provided by the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (Research Triangle Park, NC, USA). The study objective was to use microarray gene expression data acquired from the liver of rats exposed to hepatotoxi...
ORGANISM(S): Rattus norvegicus 
2010-09-25 | E-GEOD-24363 | biostudies-arrayexpress
TranscriptomicsMAQC-II Project: Hamner data set
The Hamner data set (endpoint A) was provided by The Hamner Institutes for Health Sciences (Research Triangle Park, NC, USA). The study objective was to apply microarray gene expression data from the lung of female B6C3F1 mice exposed to a 13-week treatment of chemicals to predict increased lung tum...
ORGANISM(S): Mus musculus 
2010-09-10 | E-GEOD-24061 | biostudies-arrayexpress
TranscriptomicsMAQC
The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and analysis issues. We demonstrate the consistency of results within a platform across test sites as well as the high level of cross-platform concordance in terms of genes identified ...
ORGANISM(S): Homo sapiens 
2006-12-04 | E-TABM-132 | biostudies-arrayexpress
TranscriptomicsIdentification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq
Many diseases and adverse drug reactions exhibit tissue specificity. To better understand the tissue-specific expression characteristics of transcripts in different human tissues, we deeply sequenced RNA samples from 14 different human tissues. After filtering many lowly expressed transcripts, 24,72...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-83115 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human neuroblastomas: MAQC-II project quality control phase II
The MAQC-II Project: A comprehensive study of common practices for the development and validation of microarray-based predictive models The second phase of the MicroArray Quality Control (MAQC-II) project evaluated common practices for developing and validating microarray-based models aimed at pred...
ORGANISM(S): Homo sapiens 
2010-02-04 | E-GEOD-16716 | biostudies-arrayexpress
UnknownTranscription profiling by array of human neuroblastomas: MAQC-II project quality control phase II
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-16716 | biostudies-other
TranscriptomicsA rat RNA-Seq transcriptomic Bodymap across eleven organs and four developmental stages
The rat has been used extensively as a model for evaluating chemical toxicities and for understanding drug mechanisms. However, its transcriptome across multiple organs, or developmental stages, has not yet been reported. Here we show, as part of the SEQC consortium efforts, a comprehensive rat tran...
ORGANISM(S): Rattus norvegicus 
2014-02-14 | E-GEOD-53960 | biostudies-arrayexpress
TranscriptomicsEvaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples
The Affymetrix GeneChip® system is a commonly used platform for microarray analysis but the technology is inherently expensive. Unfortunately, changes in experimental planning and execution, such as the unavailability of previously anticipated samples or a shift in research focus, may render signifi...
ORGANISM(S): Homo sapiens 
2010-09-02 | E-GEOD-23906 | biostudies-arrayexpress
TranscriptomicsMAQC-II Project: human breast cancer (BR) data set
The human breast cancer (BR) data set (endpoints D and E) was contributed by the University of Texas M. D. Anderson Cancer Center (MDACC, Houston, TX, USA). Gene expression data from 230 stage I-III breast cancers were generated from fine needle aspiration specimens of newly diagnosed breast cancers...
ORGANISM(S): Homo sapiens 
2010-02-04 | E-GEOD-20194 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of MCF-7 cells treated with Si-Wu-Tang, estradiol and ferulic acid
Traditional Chinese medicines (TCM), usually composed of a mixture of components, may simultaneously target multiple genes/pathways and thus achieve superior efficacy for complex diseases such as cancer. To identify novel mechanisms of action and potential health benefits for a TCM formula Si-Wu-Tan...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-GEOD-23610 | biostudies-arrayexpress
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