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ProteomicsNovel SLCO2B1 mRNA isoform acts as a noncoding RNA and drives cancer progression through FMR1-mediated protein biosynthesis
The eukaryotic 5’ untranslated region (5’ UTR) canonically influences mRNA translation efficiency. However, the role of the 5’ UTR structure in blocking mRNA translation and turning a coding RNA into a noncoding RNA remains undocumented. Herein, we discovered a novel mRNA isoform of the human solute...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD071347 |
ProteomicsThe NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice
To investigate protein expression differences in the ischemic brain between mice treated with vehicle and MLN4924, high-throughput proteomics Liquid Chromatography-Mass Spectrometry (LC-MS)-based analysis was performed.
ORGANISM(S): Mus Musculus 
2021-11-25 | PXD029910 |
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