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UnknownNew polymorphism in the 5' flanking region of IGF-1 gene and its association with wool traits in Egyptian Barki sheep.
Insulin-like growth factor-1 gene (IGF-1) is considered as a major candidate gene for the economic traits of animal production. Polymorphism of 5' flanking region of IGF-1 gene in Barki sheep (n = 91) and its association with wool traits were studied using the polymerase chain reaction...
S-EPMC6296639 | biostudies-literature
UnknownShort course of dutasteride in treatment of a refractory category IIIB chronic prostatitis (A placebo-controlled study).

Objective

To evaluate the short-term efficacy of Dutasteride in the management of chronic prostatitis (CP)/chronic pelvic pain syndrome.

Materials and methods

A randomized placebo-controlled double-blind study was conducted that including 50 patients diagnosed with CP based on the pre...
S-EPMC9747604 | biostudies-literature
UnknownLaser vs. bipolar prostate vaporization in bleeding-prone patients: a randomized trial and cutting-edge analysis.

Purpose

To compare effectiveness and safety of transurethral diode laser vaporization of prostate (diode LVP) versus bipolar transurethral vaporization of prostate (B-TUVP) in symptomatic benign prostatic hyperplasia (BPH) patients receiving oral anticoagulants/anti-platelet drugs.

Patien...

S-EPMC12102097 | biostudies-literature
UnknownRoutine point-of-care ultrasound (POCUS) assessment of gastric antral content in traumatic emergency surgical patients for prevention of aspiration pneumonitis: an observational clinical trial.

Background

Polytrauma patients are at a higher risk of delayed gastric emptying. To assess the gastric volume, a reliable diagnostic tool is needed to prevent the occurrence of aspiration pneumonia, which remains a serious complication associated with anesthesia. Gastric antral ultrasound ca...
S-EPMC8106174 | biostudies-literature
Unknown[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice.
Despite the advances made in cancer therapeutics, their adverse effects remain a major concern, putting safer therapeutic options in high demand. Since chalcones, a group of flavonoids and isoflavonoids, act as promising anticancer agents, we aimed to evaluate the in vivo anticancer activity of a sy...
S-EPMC9467967 | biostudies-literature
UnknownApoptosis and oxidative stress as relevant mechanisms of antitumor activity and genotoxicity of ZnO-NPs alone and in combination with N-acetyl cysteine in tumor-bearing mice.
Background: Several in vitro studies have revealed that zinc oxide nanoparticles (ZnO-NPs) were able to target cancerous cells selectively with minimal damage to healthy cells. Purpose: In the current study, we aimed to evaluate the antitumor activity of ZnO-NPs in Ehrlich solid carcin...
S-EPMC6549730 | biostudies-literature
UnknownAssociation of PRLR, IGF1, and LEP genes polymorphism with milk production and litter size in Egyptian Zaraibi goat.
Studying variation in genes responsible for physiological characters is important to enhance goat productive and reproductive efficiency. This study aimed to detect specific nucleotide polymorphisms in prolactin receptor (PRLR), insulin-like growth factor (IGF1), and leptin (LEP) genes and their cor...
S-EPMC9512711 | biostudies-literature
UnknownPredictive urinary RNA biomarkers of kidney injury after extracorporeal shock wave lithotripsy.

Background

Extracorporeal shock wave lithotripsy (ESWL) is considered one of the best choices for the treatment of various kinds of urinary tract calculi, although it might cause acute kidney injury.

Objective

To measure the urinary long non-coding RNA-messenger RNA (LncRNA-mRNA) pane...
S-EPMC9166822 | biostudies-literature
UnknownElucidating the Environmental and Health Risks of Trace Element Pollution in Red Sea Fish from Nuweiba City, Aqaba Gulf, Egypt.
Trace element bioaccumulation in marine organisms is a rising international issue due to possible health concerns for humans. Thirteen trace elements were analyzed in the sediment, water, and muscular tissue of Red Sea fish. Additionally, the average daily intake (EDI), the cancer risk (CR), the haz...
S-EPMC11872992 | biostudies-literature
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