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To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
Under well-defined laboratory conditions, we grew R. pomeroyi DSS-3 and A. macleodii MIT1002 in batch cultures on a monosaccharide (glucose) and organic acid (acetate), provided either individually or in combination, and all at the same carbon equivalent. This batch culturing approach mimicked bacte...
ORGANISM(S): Alteromonas macleodii Ruegeria pomeroyi DSS-3 Bacteria 
2023-10-27 | PXD045824 | Pride
Severe loss-of-function alleles of DCL1 are embryonic lethal. Defects in cell division were seen as early as the globular stage in the strong loss-of-function allele dcl1-15. Phenotypic work with dcl1-15 and the null allele dcl1-5 suggested that, in addition to the severe patterning defects, the m...
ORGANISM(S): Arabidopsis thaliana 
Respiratory failure and mortality from COVID-19 result from virus- and inflammation-induced lung tissue damage. The intestinal microbiome and associated metabolites are implicated in immune responses to respiratory viral infections, however their impact on progression of severe COVID-19 remains uncl...
2023-05-02 | MTBLS5288 | MetaboLights
We sought to apply the technologies of gene expression profiling to detect genes significant in the aetiology of cervical carcinoma . We investigated 14 normal (NAD), 11 low grade squamous intrapepithelial lesions (LSIL), 21 high grade squamous intraepithelial lesions (HSIL) and 28 squamous cell ca...
ORGANISM(S): Homo sapiens 
DNA lesions encountered by replicative polymerases threaten genome stability and cell cycle progression. Here we report the identification of mutations in TRAIP, encoding an E3 RING ubiquitin ligase, in patients with microcephalic primordial dwarfism/Seckel syndrome. We establish that TRAIP relocali...
Dissolved organic matter extracts prepared by viral lysates of Ostreococcus lucimarinus CCMP2972, infected by lytic viruses OlV1 and OlV7, as well as uninfected controls, under standard-light (~110uE/m2s; "SL") and low-light (15uE/m2s, "LL") irradiance.
ORGANISM(S): Ostreococcus Lucimarinus Cce9901 (ncbitaxon:436017) Ostreoccus Lucimarinus Virus Olv7 Ostreococcus Lucimarinus Virus 1 (ncbitaxon:880162) 
2019-02-12 | MSV000083434 | MassIVE
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