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A short ORF-encoded transcriptional regulator
Recent technological advances have expanded the annotated protein coding content of mammalian genomes, as hundreds of previously unidentified, short open reading frame (ORF)-encoded peptides (SEPs) have now been found to be translated. Although several studies have identified important physiological...
ORGANISM(S): Homo sapiens 
2021-01-11 | GSE164239 | GEO
Long noncoding RNA (lncRNA) refers to the family of RNA transcripts with more than 200 nucleotides in length, but cannot encode proteins. lincRNA (long intergenic noncoding RNA) is a subset of lncRNA that do not overlap with known genes. Increasing evidences have shown that some of these transcripts...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-12 | PXD013892 | Pride
Proteogenomics and ribosome profiling concurrently show that genes may code for both a large and one or more small proteins translated from annotated coding sequences (CDSs) and unannotated alternative open reading frames (named alternative ORFs or altORFs), respectively, but the stoichiometry betwe...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD008147 | Pride
RNA-Seq reads and TopHat (Trapnell et al. Bioinformatics 2009) alignments of K562 cell-line transcriptome. These were used to validate the expression of short peptides idenitified by Mass-Spectrometry in K562 cells. K562 polyA+ RNA (Batch 1) and total RNA (batch 2) was purchased from Ambion. We use...
ORGANISM(S): Homo sapiens 
Viral genomes encode large numbers of short open reading frames whose products (microproteins) remain largely uncharacterized. To assay their cellular consequences at scale, we assembled an enriched viral microprotein ORF library in the doxycycline-inducible pANDORA lentiviral vector and delivered i...
ORGANISM(S): Homo sapiens 
2026-08-21 | GSE344535 | GEO
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