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GenomicsShugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere
To protect against aneuploidy, chromosomes must attach to microtubules from opposite poles (“biorientation”) prior to their segregation during mitosis. Biorientation relies on the correction of erroneous attachments by the aurora B kinase, which destabilizes kinetochore-microtubule attachments that ...
ORGANISM(S): Saccharomyces cerevisiae W303 
2014-01-08 | GSE53856 | GEO
ProteomicsA Siz1/Siz2-mediated SUMOylation programme inactivates the shugoshin-associated phosphatase-kinase network to stabilize sister kinetochore biorientation
The accurate segregation of chromosomes during mitosis relies on the attachment of sister chromatids to microtubules from opposite poles, called biorientation. Sister chromatid cohesion resists microtubule forces, generating tension which provides the signal that biorientation has occurred. How tens...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-03-25 | PXD019287 | Pride
Chromosome segregation Mitosis Shugoshin 
UnknownShugoshin protects cohesin complexes at centromeres.
Not available
S-EPMC1569468 | biostudies-literature
UnknownA role for Shugoshin in human cilia?
Not available
S-EPMC10751581 | biostudies-literature
GenomicsShugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere
To protect against aneuploidy, chromosomes must attach to microtubules from opposite poles (“biorientation”) prior to their segregation during mitosis. Biorientation relies on the correction of erroneous attachments by the aurora B kinase, which destabilizes kinetochore-microtubule attachments that ...
ORGANISM(S): Saccharomyces cerevisiae W303 
2014-01-08 | E-GEOD-53856 | biostudies-arrayexpress
UnknownShugoshin is a Mad1/Cdc20-like interactor of Mad2.
Not available
S-EPMC3160248 | biostudies-literature
UnknownCohesin-protein Shugoshin-1 controls cardiac automaticity via HCN4 pacemaker channel.
Not available
S-EPMC8100125 | biostudies-literature
UnknownThe Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia.
Not available
S-EPMC10256747 | biostudies-literature
UnknownStructure and function of the PP2A-shugoshin interaction.
Not available
S-EPMC2749713 | biostudies-literature
UnknownShugoshin Is Essential for Meiotic Prophase Checkpoints in C. elegans.
Not available
S-EPMC6200582 | biostudies-literature
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