Sort   by:  
 Page size 
Dystrophin Dp71 is the main product of the DMD (Duchenne muscular dystrophy) gene in the brain. Dystrophin Dp71 is essential for the development of the nervous system and its alteration is associated with intellectual disability. Different isoforms of Dp71, with different subcellular locations, are ...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-11-01 | PXD021886 | Pride
Toxoplasma gondii is an obligate intracellular parasite. The ability to invade cells and proliferate successfully is given by the machinery found in the pellicle of the parasite, the pellicle is a complex of three membranes. Despite the importance of the pellicle in the biology of Toxoplasma, its pr...
ORGANISM(S): Toxoplasma gondii 
2021-02-16 | PXD022398 | Pride
Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
Obstructive nephropathy (ON) is a common clinical entity caused by different etiologies such as urolithiasis, prostatic hyperplasia in males, tumors, congenital stenosis, and others. Unilateral ureteral obstruction (UUO) in rodents is an experimental model widely used to explore the pathophysiology ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-18 | PXD036205 | Pride
Extracting histones from cells is a routine operation for studies that aim to characterize histones and their post-translational modifications (hPTMs). However, label-free quantitative mass spectrometry (MS) approaches, both data-dependent (DDA) and data-independent (DIA), require streamlined protoc...
ORGANISM(S): Homo sapiens (Human) 
2016-10-11 | PXD002885 | Pride
The Göttingen Minipig is gaining ground as nonrodent species in safety testing of drugs for pediatric indications. Due to developmental changes in pharmacokinetics (PK) and pharmacodynamics (PD), physiologically-based pharmacokinetic (PBPK) models are built to better predict drug exposure in childre...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-02-26 | PXD024158 | Pride
Sort   by:  
 Page size