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ProteomicsAffinity purification of the Legionella effector SidL in HEK293T cells
Legionella pneumophila is an intracellular bacterial pathogen that encodes almost 300 effector proteins, many of which target various aspects of its eukaryotic host. While the physiological roles of many effectors are not understood, the focused study of individual effectors provides insight into th...
ORGANISM(S): Homo sapiens (Human) 
2026-07-24 | PXD068090 | Pride
Legionella pneumophila Actin Sidl 
ProteomicsGWI Mouse model SIDL - Complementary proteomic approaches reveal mitochondrial dysfunction, immune and inflammatory dysregulation in a mouse model of gulf war illness
Long term consequences of combined pyridostigmine bromide and permethrin exposure in C57BL6/J mice using a well characterized mouse model of exposure to these Gulf War agents. Expanding on earlier work, we used orthogonal proteomic approaches to identify pathways that are chronically impacted in the...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-01 | PXD005198 | Pride
Sidl Gwi Mouse model Gulf war illness 
UnknownSidL, an Aspergillus fumigatus transacetylase involved in biosynthesis of the siderophores ferricrocin and hydroxyferricrocin.
Not available
S-EPMC3147410 | biostudies-literature
UnknownCrystal structure of the <i>Legionella pneumophila</i> effector SidL (Lpg0437) in complex with its metaeffector LegA11 (Lpg0436).
Not available
S-EPMC12633379 | biostudies-literature
ProteomicsGulf War Illness mouse model chronic iTRAQ
Long term consequences of combined pyridostigmine bromide and permethrin exposure in C57BL6/J mice using a well characterized mouse model of exposure to these Gulf War agents. Expanding on earlier work, we used orthogonal proteomic approaches to identify pathways that are chronically impacted in the...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-01 | PXD005185 | Pride
Mouse model Itraq Chronic Gulf war illness Quantitative proteomics 
UnknownSidF, a dual substrate N5-acetyl-N5-hydroxy-L-ornithine transacetylase involved in Aspergillus fumigatus siderophore biosynthesis.
Not available
S-EPMC11751504 | biostudies-literature
UnknownTargeting Eukaryotic mRNA Translation by Legionella pneumophila.
Not available
S-EPMC7201127 | biostudies-literature
UnknownFungal-Mineral Interaction: Astrobiology Insights from Iron-Rich Mineral Alteration by an Extremophile Black Fungus.
Not available
S-EPMC12848704 | biostudies-literature
TranscriptomicsSecreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila [exp2]
The intracellular bacterial pathogen Legionella pneumophila causes an inflammatory pneumonia called Legionnaires’ Disease. For virulence, L. pneumophila requires a Dot/Icm type IV secretion system that translocates bacterial effectors to the host cytosol. L. pneumophila lacking the Dot/Icm system ...
ORGANISM(S): Mus musculus 
2011-01-08 | E-GEOD-26490 | biostudies-arrayexpress
GenomicsCoupling ER stress to STAT1-mediated immunity against bacterial infection
Coupling ER stress to STAT1-mediated immunity against bacterial infection
PRJNA1214396 | ENA
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