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TranscriptomicsWhole genome scanning of lung tumors and mucosal biopsies on Affymetrix NspI-250K platform
Matched normal lymph node, tumors and corresponding mucosal biopsies from 4 lung cancer patients were scrutinized on Affymetrix 250K-NspI array platform. Frequently deleted regions genes were identified based on the LOH call as per manufacturer's guidelines and normalization. Frequently deleted gene...
ORGANISM(S): Homo sapiens 
2013-01-11 | E-GEOD-29365 | biostudies-arrayexpress
TranscriptomicsExpression data identifying hypermethylated genes associated with acquired cisplatin resistance
Treatment-related DNA hypermethylation may play a role in creating drug resistant phenotypes by inactivating genes that are required for cytotoxicity, but there have been no genome-wide studies to systematically investigate methylation of individual genes following exposure to chemotherapy. We used ...
ORGANISM(S): Homo sapiens 
2010-04-12 | E-GEOD-19397 | biostudies-arrayexpress
TranscriptomicsIdentification of GNG7 as An Epigenetically Silenced Gene in Head and Neck Cancer by Gene Expression Profiling
Silencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. Aberrant hypermethylation in the promoter region of some known or putative tumor suppressor genes (TSGs) occurs frequently during the development of various cancers including head and neck squamous cell carcinoma...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-29330 | biostudies-arrayexpress
ProteomicsMolecular characterization of esophageal squamous cell carcinoma using quantitative proteomics
Esophageal squamous cell carcinoma (ESCC) is a heterogeneous cancer associated with high mortality rate. In India, it is the 6th most common cause of cancer-related mortality. In this study, we employed high-resolution mass spectrometry-based quantitative proteomics to characterize differential prot...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD036238 | Pride
Quantitative proteomics Cell cycle regulation Syvn1 Esophageal squamous cell carcinoma Er stress 
ProteomicsiTRAQ-based quantitative proteomics analysis of human HNSCC cells
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer and is major cause of cancer mortality and morbidity. It emerges within oral cavity, lip, tongue, floor of the mouth, nasopharynx, palate, gingival and larynx, is common cancer worldwide especially in Southeast Asia and So...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-14 | MSV000079580 | MassIVE
TranscriptomicsNID2 and HOXA9 promoter hypermethylation as biomarkers to prevent and detect Oral Cavity Squamous Cell Carcinoma
Differentially methylated oral squamous cell carcinoma (OSCC) biomarkers, identified in-vitro and validated in well-characterized surgical specimens, have shown poor clinical correlation in cohorts with different risk profiles. To overcome this lack of relevance we used the HumanMethylation27 BeadCh...
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-28217 | biostudies-arrayexpress
UnknownThe KRAS-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer: A Secondary Analysis of a Randomized Clinical Trial.
Not available
S-EPMC5470422 | biostudies-literature
TranscriptomicsIntegrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma
Salivary gland adenoid cystic carcinoma (ACC) is a rare malignancy amongst head and neck tumors that is poorly understood on a molecular level. We sought to perform a comprehensive approach for novel oncogene candidate screening under the control of promoter methylation in order to learn more about ...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-25746 | biostudies-arrayexpress
UnknownDiscovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.
Not available
S-EPMC5282828 | biostudies-literature
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