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ProteomicsElucidation of B-cell specific drug immunogenicity liabilities via a novel ex vivo assay
The appended raw files, csv files and other documents were deposited in the public domain in support for the publication "Elucidation of B-cell specific drug immunogenicity liabilities via a novel ex vivo assay" by Cary M Looney, Axel Ducret, Guido Steiner, Karen Dernick, Katharina Hartman, Michel S...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-02-19 | MSV000097151 | MassIVE
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
ProteomicsExpanding the MAPPs assay to accommodate MHC-II pan re-ceptors for improved predictability of potential T cell epitopes
The appended raw files, csv files and other documents were deposited in the public domain in support for the publication "Expanding the MAPPs assay to accommodate MHC-II pan re-ceptors for improved predictability of potential T cell epitopes" by Katharina Hartman, Guido Steiner, Michel Siegel, Cary ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-25 | MSV000092747 | MassIVE
ProteomicsInternalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Internalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity" by Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-26 | MSV000095695 | MassIVE
ProteomicsDevelopment and qualification of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Development and characterization of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics" by Michel Siegel, Aman Padamse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-12 | MSV000095578 | MassIVE
ProteomicsAcetylation changes in NQO1 overexpression in Mouse Skeletal Mucscle
In this manuscript we have explored the role of both Nrf2 and NQO1 in protection against diet-induced metabolic syndrome and demonstrate that both Nrf2 and NQO1 provide protection against HFD-induced adverse phenotypes in a mouse model
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD015070 | Pride
Nqo1 Mouse Metabolic syndrome Quantitation Acetylomics Skeletal muscle 
UnknownPeritoneal flap for lymphocele prophylaxis following robotic-assisted laparoscopic radical prostatectomy with pelvic lymph node dissection: study protocol and trial update for the randomized controlled PELYCAN study.
Not available
S-EPMC8008541 | biostudies-literature
UnknownROBOCOP II (ROBOtic assisted versus conventional open partial nephrectomy) randomised, controlled feasibility trial: clinical trial protocol.
Not available
S-EPMC8572388 | biostudies-literature
UnknownPTPN1/PTPN2 inhibition improves NK cancer therapy by enhancing IL-2 and mitigating TGFβ1 responses
Not available
S-SCDT-10_1038-S44319-026-00745-0 | biostudies-other
UnknownA DARPin targeting activated Mac-1 is a novel diagnostic tool and potential anti-inflammatory agent in myocarditis, sepsis and myocardial infarction.
Not available
S-EPMC7960600 | biostudies-literature
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