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Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration
Siglec-F+ neutrophils in the spleen induce immunosuppression following acute infection
We used mRNA-seq analysis to explore the transcriptional response induced in BV-2 cells by stable overexpression Siglec-F and related human Siglec receptors compared to loss-of-function 2xY->F mutant receptors.
ORGANISM(S): Mus musculus 
2020-09-01 | GSE149153 | GEO
Determine anti-Siglec-F and IL-33 costimulation induced transcriptional changes on murine eosinophils
Siglec-F Protects Against Elastase-induced Lung Inflammation and Emphysema in Mice
Gene expression profile of Siglec F+ alveolar macrophages under conditions of liver regeneration after 70% resection.
The mechanisms underlying the increased mortality of secondary infections during the immunosuppressive phase of sepsis remain elusive. We established a mouse model of sepsis-induced immunosuppression followed by secondary infection. Compared to other organs, we observed a significant reduction in pr...
ORGANISM(S): Mus musculus 
2024-04-24 | GSE264139 | GEO
The aim of the work was to study the expression profile of Siglec F+ alveolar macrophages under conditions of liver regeneration after 70% resection. We used microarrays for comparison of Siglec F+ alveolar macrophages in intact mice and in mice under conditions of liver regeneration after 70% resec...
ORGANISM(S): Mus musculus 
2026-05-01 | GSE322399 | GEO
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