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Although immediate early genes (IEGs) such as Bdnf, Arc and Egr1, have been implicated in plasticity, the larger pathways related to memory and memory disorders are not well understood. Here, we combined statistical Affymetrix microarray and behavioral analyses to identify key genes and pathways ass...
ORGANISM(S): Rattus norvegicus 
Male Fischer 344 rats aged 4 months (young, n=10), 14 months (mid-aged, n=10), and 24 months (aged, n=10) were trained sequentially on two tasks: Morris Spatial Water Maze (SWM) and Object Memory Task (OMT). The training/testing sequence lasted 7 d, and hippocampal tissue was collected 24 hr later. ...
ORGANISM(S): Rattus norvegicus 
Micorarray analysis was performed on RNA samples from hippocampal cultures infected with either Ad-aCaN or Ad-LacZ or uninfected. Each sample was applied to its own GeneChip (Rat RG-U34A; n=7-9 chips/group). Chips were then processed and scanned using Agilent Affymetrix GeneArray Scanner. MAS5 was u...
ORGANISM(S): Rattus norvegicus 
The model is based on MODEL1905220001 but has two compartments that have different composition of the biosynthetic enzymes NADA and NamPT. One compartment contains in addition NNMT, the other one does not. Both compartments are competing for a common Nam source.
2019-08-01 | MODEL1905220002 | BioModels
Analysis of global gene transcription profile of wild type MC58 and nadR deletion mutant strains grown in GC until mid log phase
ORGANISM(S): Neisseria meningitidis 
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