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TranscriptomicsGenome-wide effect of Galectin-7 ectopic expression in HeLa and SiHa cervical cancer cell lines.
The Galectin-7 gene has been found subregulated in several cervical cancer cell lines and in clinical samples. To study the changes in the cell system after the ectopic expression of Galectin-7, we used microarrays to analyze transcriptome of HeLa and SiHa cancer cell line. Cells were transfected wi...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-MTAB-3306 | biostudies-arrayexpress
TranscriptomicsGenome-wide effect of the microenvironment over the Galectin-7 regulation network in HeLa and SiHa tumors in nude mice.
Galectin-7 transfected HeLa and SiHa cells and controls were implanted in Balb/c mice to generate tumors, we perform microarrays to analyze transcriptome of HeLa and SiHa Galectin-7 positive and controls tumors in 3 biological replicates to study the microenvironment influence in the Galectin-7-rela...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-MTAB-3307 | biostudies-arrayexpress
GenomicsRNA-Seq of H8, SiHa and KD HSPA9 SiHa cells
RNA-Seq of H8, SiHa and KD HSPA9 SiHa cells
PRJNA986457 | ENA
TranscriptomicsComparison of transcriptome of SiHa-N (with pcDNA3 backbone vector) and SiHa-R (with RhoC over-expressing plasmid)
Since RhoC is known to be involved in various tumour phenotypes, a transcriptome analysis was carried out with RhoC over-expressing cells to identify the genes altered by RhoC over-expression.
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-12162 | biostudies-arrayexpress
GenomicsChIP seq of SiHa RhoC overexpressing cells with RhoC and WDR5 antibodies
The aim of the experiment was to identify regions of DNA bound by RhoC and WDR5. SiHa cells overexpressing RhoC were crosslinked, digested with MNase and sonicated. The fragmented DNA that bound to RhoC and WDR5 was pulled down using RhoC and WDR5 antibodies and sequenced using the Illumina HiSeq pl...
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-12164 | biostudies-arrayexpress
ProteomicsTMT Screening of Human Samples:SiHa cell
A screen for APOA1 downstream proteins affecting platinum-based chemoresistance using Tandem Mass Tag revealed 64 differentially expressed proteins in SiHa cells, which were subjected to Gene Ontology (annotation, Kyoto Encyclopedia of Genes and Genomes enrichment, subcellular localization, structur...
ORGANISM(S): Cancer 
2022-05-20 | PXD030885 | Pride
Siha cell Tmt screening Human samples 
GenomicsRNA-seq analysis of CaSki/SiHa/HeLa cell lines
RNA-seq analysis of CaSki/SiHa/HeLa cell lines
PRJNA663801 | ENA
ProteomicsQuantitative proteomic study of two cervical cancer cell lines upon re-expression of Galectin 7
Galectin-7 expression was found to be strongly reduced in cervical cancer cell lines. The same tumor cell lines in which Galectin-7 was ectopically expressed exhibited significant decrease in their tumorigenic capacity in vitro and in vivo. The proteomic changes in the cervical cancer cell lines HeL...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080855 | MassIVE
GenomicsChIP-Seq hnRNP E1, Cervical cancer SiHa cells
ChIP-Seq hnRNP E1, Cervical cancer SiHa cells
PRJNA838137 | ENA
TranscriptomicsMethylation profiling of RhoC over-expressing SiHa cells (SiHa-R) against SiHa cells with backbone vector alone (SiHa-N)
Since we have found that the RhoC gene causes extensive changes to gene expression, a methylation array was carried out to determine if the observed transcriptional changes are due to methylation changes in the genome.
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-12125 | biostudies-arrayexpress
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