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GenomicsTranscriptome analysis of liver sinusoidal endothelial cells (LSECs) under palmitic acid treatment and IL-6/sIL-6R complex stimulation
Transcriptome analysis of liver sinusoidal endothelial cells (LSECs) under palmitic acid treatment and IL-6/sIL-6R complex stimulation
PRJNA1292756 | ENA
TranscriptomicsTranscriptome analysis of liver sinusoidal endothelial cells (LSECs) under palmitic acid treatment and IL-6/sIL-6R complex stimulation
This study investigates the transcriptional changes in liver sinusoidal endothelial cells (LSECs) following palmitic acid (PA) treatment and IL-6/sIL-6R complex stimulation. LSECs were cultured with PA for 12 hours and subsequently stimulated with the IL-6/sIL-6R complex for 1 hour to assess trans-s...
ORGANISM(S): Homo sapiens 
2026-04-01 | GSE302884 | GEO
UnknownThe balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.
Not available
S-EPMC5936821 | biostudies-literature
UnknownEZH2 promotes angiogenesis in peritoneal dialysis by epigenetically activating SP4 expression in the IL-6/sIL-6R signalling pathway.
Not available
S-EPMC9812808 | biostudies-literature
UnknownHGF, sIL-6R and TGF-β1 Play a Significant Role in the Progression of Multiple Myeloma.
Not available
S-EPMC4067511 | biostudies-literature
UnknownFungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts.
Not available
S-EPMC6260243 | biostudies-literature
UnknownEvolution of a bispecific G-quadruplex-forming circular aptamer to block IL-6/sIL-6R interaction for inflammation inhibition.
Not available
S-EPMC11323322 | biostudies-literature
UnknownAn intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification.
Not available
S-EPMC3257015 | biostudies-literature
UnknownPre-diagnostic levels of sVEGFR2, sTNFR2, sIL-2Rα and sIL-6R are associated with glioma risk: A nested case-control study of repeated samples.
Not available
S-EPMC8855896 | biostudies-literature
UnknownHDAC6-dependent deacetylation of TAK1 enhances sIL-6R release to promote macrophage M2 polarization in colon cancer.
Not available
S-EPMC9587286 | biostudies-literature
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