Silencing - OmicsDI

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Unknown (33676)
Genomics (10974)
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Methylation profiling (388)
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Organisms

Homo sapiens (4655)
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cellular organisms (5)
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Organisms

Homo sapiens (2815)
Mus musculus (1803)
Arabidopsis thaliana (439)
Drosophila melanogaster (294)
Caenorhabditis elegans (175)
Schizosaccharomyces pombe (131)
Saccharomyces cerevisiae (81)
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unidentified (9)
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Tetrahymena thermophila (7)

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Mass Spectrometry (513)
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ESI (4)
MSE (4)
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ILLUMINA, Illumina HiSeq 2500 (1)
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PromethION (4)
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418 [Affymetrix] (4)
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2100 Bioanalyzer (2)
BAS-5000 [FUJIFILM] (2)
ScanArray Express HT [PerkinElmer] (2)
G2505B DNA microarray scanner (2)
Illumina NovaSeq X (2)
DNBSEQ-G400 (2)
MinION (2)

Publication Date

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2019 (467)
2017 (398)
2018 (369)
2008 (345)
2009 (304)
2007 (134)
2006 (65)
2005 (32)
2004 (10)
2003 (5)

UNIPROT ID/AC

Q9UJX3 (2)
Q9UJX2 (2)
Q9UJX4 (2)
Q9UM13 (2)
Q8NHZ8 (2)
Q9H1A4 (2)
P30260 (2)
Q9BS18 (2)
Q9NYG5 (2)
Q9UJX6 (2)
Q9UJX5 (2)
Q13042 (2)
Q60566 (2)
O43684 (2)
Q12834 (2)
Q13257 (2)
Q9Y6D9 (2)
P16104 (1)
Q93009 (1)
Q06587 (1)
P35226 (1)
P25302 (1)
P00546 (1)
P08153 (1)
P11746 (1)
P20437 (1)
P38634 (1)
P24868 (1)
A0A067FZ61_CITSI (1)
A0A067GQV1_CITSI (1)

ENSEMBL ID

ENSG00000170477 (9)
ENSG00000247315 (6)

CHEBI ID

CHEBI:30769 (9)
CHEBI:18012 (8)
CHEBI:15741 (7)
CHEBI:16335 (7)
CHEBI:16704 (7)
CHEBI:16737 (7)
CHEBI:17659 (6)
CHEBI:16436 (6)
CHEBI:22660 (6)
CHEBI:16708 (6)
CHEBI:16750 (6)
CHEBI:15428 (6)
CHEBI:6650 (6)
CHEBI:7916 (6)
CHEBI:30915 (6)
CHEBI:17596 (6)
CHEBI:15682 (5)
CHEBI:26271 (5)
CHEBI:17287 (5)
CHEBI:17858 (5)
CHEBI:15346 (5)
CHEBI:22653 (5)
CHEBI:18186 (5)
CHEBI:16811 (5)
CHEBI:28300 (5)
CHEBI:18257 (5)
CHEBI:16742 (5)
CHEBI:17724 (5)
CHEBI:17562 (5)
CHEBI:17148 (5)

Metabolite Name

Creatinine (8)
Adenosine (7)
L-Lysine (6)
Threonine (6)
Adenine (6)
Uric acid (6)
L-Serine (6)
Uridine (6)
Inosine (6)
Malate (5)
ATP (5)
Uracil (5)
Betaine (5)
L-Aspartic acid (5)
Diethanolamine (5)
ADP (5)
L-Asparagine (5)
L-Threonine (5)
Pantothenic acid (5)
L-Histidine (5)
Methionine (5)
Choline (5)
Fumaric acid (5)
Xanthosine (5)
Tyrosine (5)
N-Acetylputrescine (5)
Suberic acid (5)
Riboflavin (5)
Porphobilinogen (5)
L-Tryptophan (5)

First Public Date

2014 (952)
2025 (866)
2024 (865)
2026 (818)
2023 (660)
2020 (510)
2021 (502)
2022 (500)
2019 (469)
2017 (388)
2018 (374)
2013 (350)
2015 (311)
2016 (256)
2012 (4)
2011 (2)

Modelling Approach

Ordinary differential equation model (6)
Mathematical model (1)
Other (1)

Study status

Not provided (1)

Lab affiliation

Moffitt Cancer Center Tampa, FL, USA (11)
IMB, Ackermannweg 4, 55128 Mainz (5)
CRUK Cambridge Institute University of Cambridge Li Ka Shing Centre Robinson Way CB2 0RE Cambridge United Kingdom (4)
Laboratoire de Spectrometrie de Masse Proteomique Institut Curie PSL Research University (4)
Department of Chemistry, National and Kapodistrian University of Athens, 15784 Zografou, Greece (4)
University of Edinburgh (4)
Head of the Curie Institute Mass Spectrometry Platform (4)
Proteomics and Metabolomics Unit, Monzino Cardiologic Center, IRCCS, Milan, Italy (3)
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, 792 Elizabeth Street, Melbourne, VIC 3000, Australia. (3)
Department of Microbiology and Immunology, The University of Melbourne, Victoria, Australia (3)
UCLA (3)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (3)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (3)
Drug Discovery Moffitt Cancer Center Tampa, FL, USA (3)
Institute of Molecular Biology (IMB) (3)
University of Dundee (3)
Cornell University (3)
Genome Regulation, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland (2)
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) Beutenbergstraße 11 07745 Jena, Germany (2)
IMBA - Institute of Molecular Biotechnology Dr. Bohrgasse 3 1030 Vienna Austria (2)
Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria. (2)
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Cambridge CB2 0RE United Kingdom (2)
changzhi medical college (2)
South China Agricultural University (2)
Biological Chemistry and Drug Discovery Unit, School of Life Sciences, University of Dundee (2)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands Division of Molecular Genetics, The Netherlands Cancer Institute, 1066CX, Amsterdam, The Netherlands (2)
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Cambridge CB2 0RE United Kingdom (2)
Professor of Molecular Biology. Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee ,Dundee, DD1 5EH, Scotland, UK (2)
Institute of Molecular Biology Ackermannweg 4 55128 Mainz (2)
Chronic Disease Programme, UFIEC, Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain. (2)

IsPrivate

False (8)

Classification

protozoa (39)
bacteria (30)
fungi (29)
viruses (7)
helminths (4)

Modification

2x(15)N labeled L-lysine (3)
N6 (2)
4x(15)N labeled L-arginine (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (2113)
RNA-seq of coding RNA (607)
ChIP-chip by tiling array (599)
ChIP-seq (589)
RNA-seq of non coding RNA (401)
Methylation profiling by high throughput sequencing (102)
RNAi profiling by array (94)
Methylation profiling by array (94)
Other (74)
Unknown experiment type (60)
Transcription profiling by tiling array (38)
Comparative genomic hybridization by array (36)
ChIP-chip by array (32)
Cell line - High-throughput sequencing (20)
MicroRNA profiling by array (20)
RNA-seq of total RNA (19)
DNA-seq (17)
Transcription profiling by RT-PCR (13)
RNA-seq of coding RNA from single cells (11)
Genotyping by array (10)
Plant - High-throughput sequencing (8)
Animal - High-throughput sequencing (5)
RIP-seq (5)
MicroRNA profiling by high-throughput sequencing (4)
Bisulfite-seq (4)
ATAC-seq (4)
Plant - One-color microarray (3)
High-throughput sequencing (3)
CLIP-seq (3)
Transcription profiling by MPSS (2)

Release Date

2022 (3238)
2021 (3175)
2025 (2673)
2023 (2600)
2020 (2533)
2024 (2319)
2019 (2258)
2016 (2242)
2015 (2123)
2013 (2076)
2014 (2001)
2017 (1994)
2018 (1989)
2012 (1564)
2011 (1541)
2010 (1271)
2009 (801)
2008 (739)
2007 (380)
2026 (376)
2006 (281)
2005 (185)
2004 (105)
2003 (64)
2002 (64)
2001 (40)
1999 (23)
2000 (22)
1998 (6)
1997 (5)

Location

Denmark (1)

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Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis

Translation fidelity is the limiting factor in the accuracy of gene expression. With an estimated frequency of 10-4, errors in mRNA decoding occur in a mostly stochastic manner. Little is known about the response of higher eukaryotes to chronic loss of ribosomal accuracy as per an increase in the...

2019-09-17 | MTBLS106 | MetaboLights

Reversing Epigenetic Gene Silencing to Overcome Immune Evasion in CNS Malignancies

Not available

ORGANISM(S): Mus musculus

ST001838 | MetabolomicsWorkbench

Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe

Spt6 is a conserved factor, critically required for several transcription and chromatin related processes. We now show that Spt6 and its binding partner, Iws1, are required for heterochromatic silencing in Schizosaccharomyces pombe. Our studies demonstrate that Spt6 is required for silencing of al...

ORGANISM(S): Schizosaccharomyces pombe

2011-10-20 | E-MTAB-738 | biostudies-arrayexpress

Argonaute proteins couple chromatin silencing to alternative splicing

This SuperSeries is composed of the following subset Series: GSE39746: Argonaute proteins couple chromatin silencing to alternative splicing (exon array) GSE39748: Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) Refer to individual Series

ORGANISM(S): Mus musculus

2012-08-22 | E-GEOD-39749 | biostudies-arrayexpress

Genomewide view of gene silencing by small interfering RNAs

RNA interference (RNAi) is an evolutionarily conserved mechanism in plant and animal cells that directs the degradation of messenger RNAs homologous to short double-stranded RNAs termed small interfering RNA (siRNA). The ability of siRNA to direct gene silencing in mammalian cells has raised the pos...

ORGANISM(S): Homo sapiens

2005-12-14 | E-GEOD-3825 | biostudies-arrayexpress

Environment-responsive transcription factors bind proto-silencer elements and regulate subtelomeric silencing

Subtelomeric chromatin is subject to evolutionarily conserved complex epigenetic regulation and is implicated in numerous aspects of cellular function including formation of heterochromatin, regulation of different stress response pathways, and control of lifespan. Subtelomeric DNA is characterized...

ORGANISM(S): Saccharomyces cerevisiae

2011-05-02 | E-GEOD-21852 | biostudies-arrayexpress

Evidence for an RNAi-independent role of DICER-LIKE2 in conferring growth inhibition and basal antiviral resistance

Higher plants encode four or five DICER-LIKE (DCL) enzymes responsible for the production of small non-coding RNAs which function in RNA interference (RNAi). Different RNAi pathways in plants effect transposon silencing, antiviral defense and endogenous gene regulation. DCL2 acts genetically redunda...

ORGANISM(S): Arabidopsis Thaliana

2024-07-26 | PXD046163 | panorama

A SWI/SNF nucleosome remodeling complex acts in non-coding RNA-mediated transcriptional silencing

RNA-mediated transcriptional silencing prevents deleterious effects of transposon activity and controls the expression of protein-coding genes. It involves long non-coding RNAs (lncRNAs)1, which in Arabidopsis thaliana are produced by a specialized RNA Polymerase V (Pol V)2. lncRNAs guide Argonaute-...

ORGANISM(S): Arabidopsis thaliana

2012-12-01 | E-GEOD-38400 | biostudies-arrayexpress

chip in silencing suppressor plants or in mirna plants-Transcriptional and post-transcriptional changes in Arabidopsis plants that constitutively express suppressors of RNA silencing

gen107_ptgs - chip in silencing suppressor plants or in mirna plants - What are the genes that are differentially regulated in various tissues derived from silencing suppressor plants or miRNA mutants? - How are the histone modifications and the chromatin structure in miRNA mutants or in silencing s...

ORGANISM(S): Arabidopsis thaliana

2011-08-22 | E-GEOD-24692 | biostudies-arrayexpress

Transcriptional gene silencing by Arabidopsis Microrchidia homologues involves the formation of heteromers

Epigenetic gene silencing is of central importance to maintain genome integrity and is mediated by an elaborate interplay between DNA methylation, histone posttranslational modifications and chromatin remodeling complexes. DNA methylation and repressive histone marks usually correlate with transcrip...

ORGANISM(S): Arabidopsis thaliana

2014-06-01 | E-GEOD-54677 | biostudies-arrayexpress

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