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ProteomicsPlasma proteomic signature of major depressive episode in the elderly
Depression is a complex and multifactorial disease, affecting about 6.5% of the elderly population in what is referred to as late-life depression (LLD). Despite its public health relevance, there is still limited information about the molecular mechanisms of LLD. We analyzed the blood plasma of 50 o...
ORGANISM(S): Homo sapiens (Human) 
2023-03-07 | PXD034030 | Pride
Late-life depression  proteomics  aging  senescence 
ProteomicsMyocardial proteome changes in aortic stenosis rats subjected to long-term aerobic exercise
The effects of exercise training (ET) on the heart of aortic stenosis (AS) rats are controversial and the mechanisms involved in alterations induced by ET have been poorly clarified. In this study we analyzed the myocardial proteome to identify proteins modulated by moderate intensity aerobic ET in ...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-02-29 | PXD040785 | Pride
Supravalvular aortic stenosis Myocardium Ventricular dysfunction Rat Aerobic exercise training Proteomics 
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