Myocardium - OmicsDI

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Organisms

Mus musculus (426)
Homo sapiens (241)
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Marchantia polymorpha subsp. ruderalis (84)
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synthetic construct (5)
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Mus (1)

Organisms

Mus musculus (292)
Homo sapiens (116)
Rattus norvegicus (57)
Danio rerio (32)
Sus scrofa (18)
Canis lupus familiaris (4)
Oryctolagus cuniculus (3)
Ovis aries (3)
Macaca mulatta (2)
Mus (1)
Ciona intestinalis (1)
unidentified (1)
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Repository

ENA (618)
geo (538)
biostudies-arrayexpress (261)
pride (84)
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Tissue

Heart (63)
Myocardium (9)
Cell culture (8)
Cardiac muscle cell (6)
Left ventricle (4)
Mesenchymal cell (4)
Stem cell (4)
Fibroblast (4)
Cardiocyte (3)
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Extracellular vesicle (2)
Skeletal muscle (2)
Brain (2)
Lung (2)
Epithelial cell (2)
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Liver (2)
Atrial myocardium (1)
Ventricular myocardium (1)
Extra-ocular muscle (1)
Hindlimb muscle (1)
Heart (1)
Right ventricle (1)
Cervical spine (1)
Atherosclerotic plaque (1)
Extracellular matrix (1)
Cardiomyocyte cell line (1)
Cardiac endothelial cell (1)
Intestine (1)
Electrically active cell (1)

Disease

Cardiovascular system disease (17)
Myocardial ischemia (4)
Normal (3)
Heart disease (2)
Aortic valve stenosis (2)
Cardiomyopathy (2)
Acute myocardial infarction (2)
Duchenne muscular dystrophy (2)
Heart failure (2)
Type 2 diabetes mellitus (2)
Disease free (2)
Permanent atrial fibrillation (1)
Brugada syndrome (1)
Congestive heart failure (1)
Ischaemia reperfusion injury (1)
Sham surgery (1)
Viral myocarditis (1)
Diabetes mellitus (1)
Idiopathic dilated cardiomyopathy (1)
Neuroblastoma (1)
Not Available (1)
Endotoxemia (1)
Familial hypercholesterolemia (1)
Wolfram syndrome 1 (1)
Coronary artery disease (1)
Myocarditis (1)
Congenital heart disease (1)
Diastolic heart failure (1)
Aortic valve stenosis (1)
Cerebrovascular disease (1)

Technology Type

Mass Spectrometry (85)
Shotgun proteomics (46)
Bottom-up proteomics (18)
Mass spectrometry (10)
SWATH MS (8)
Data-dependent acquisition (8)
Mass spectrometry assay (7)
Gel-based experiment (4)
Data-independent acquisition (3)
HDMSE (2)
Top-down proteomics (2)
Affinity purification coupled with mass spectrometry proteomics (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
ILLUMINA, Illumina MiSeq (1)
ESI (1)
Metaproteomics (1)
Proteogenomics (1)
Affinity proteomics (1)
DiaPASEF (1)

Instrument Platform

Illumina NovaSeq 6000 (13)
NextSeq 500 (7)
Illumina HiSeq 2500 (4)
Q Exactive (4)
AB SOLiD 5500 (2)
NextSeq 2000 (2)
Illumina HiSeq 3000 (2)
Illumina HiSeq 4000 (2)
MALDI Synapt G2-S HDMS (2)
TOF/TOF 5800 (2)
TimsTOF Pro (2)
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Not applicable (1)
Illumina NovaSeq X (1)
Illumina iSeq 100 (1)
Illumina HiSeq 1000 (1)
MinION (1)
BGISEQ-500 (1)
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Ion Torrent S5 XL (1)
Illumina HiSeq 1500 (1)
Instrument (1)
Orbitrap Velos Pro (1)
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FTICR (1)
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Impact (1)
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LTQ Orbitrap Velos Pro (1)

Publication Date

2025 (111)
2026 (91)
2021 (90)
2024 (73)
2023 (63)
2022 (53)
2019 (45)
2015 (41)
2020 (41)
2016 (40)
2013 (40)
2010 (38)
2014 (37)
2011 (34)
2018 (29)
2012 (28)
2008 (25)
2017 (22)
2007 (20)
2009 (15)
2005 (9)
2006 (4)
2004 (1)
2003 (1)

CHEBI ID

CHEBI:16919 (4)
CHEBI:16761 (4)
CHEBI:16335 (4)
CHEBI:15891 (4)
CHEBI:16704 (4)
CHEBI:17345 (4)
CHEBI:16737 (4)
CHEBI:30769 (4)
CHEBI:15422 (3)
CHEBI:15611 (3)
CHEBI:17202 (3)
CHEBI:17858 (3)
CHEBI:16856 (3)
CHEBI:16708 (3)
CHEBI:16668 (3)
CHEBI:17562 (3)
CHEBI:16988 (3)
CHEBI:28842 (3)
CHEBI:6650 (3)
CHEBI:17154 (3)
CHEBI:16865 (3)
CHEBI:16196 (3)
CHEBI:17568 (3)
CHEBI:18211 (3)
CHEBI:17053 (3)
CHEBI:18012 (3)
CHEBI:16027 (3)
CHEBI:16199 (3)
CHEBI:24838 (1)
CHEBI:17287 (1)

Metabolite Name

Adenosine (5)
Adenine (5)
Creatine (5)
L-Cystine (4)
Niacinamide (4)
Creatinine (4)
Thiamine monophosphate (3)
Anserine (3)
L-citrulline (3)
Histidine (3)
L-Alanine (3)
Uracil (3)
Sphingosine (3)
L-Proline (3)
Perindopril (3)
Benzyl alcohol (3)
L-Asparagine (3)
Phosphocholine (3)
Cholesterol (3)
Pantothenic acid (3)
Adenosine 5'-monophosphate (3)
L-Glutamic acid (3)
Taurine (3)
Arginine (3)
Lysine (3)
Cytosine (3)
L-Glutamine (3)
Cytidine (3)
Guanosine (3)
Uridine (3)

IsPrivate

False (9)

First Public Date

2025 (93)
2026 (78)
2014 (74)
2024 (73)
2023 (59)
2021 (55)
2019 (48)
2022 (46)
2020 (25)
2017 (17)
2015 (17)
2018 (15)
2016 (15)
2013 (3)

Modelling Approach

Ordinary differential equation model (9)

Modification

Not available (1)

Study type

Transcription profiling by array (185)
RNA-seq of coding RNA (38)
Single nucleus RNA sequencing (6)
ChIP-seq (6)
Unknown experiment type (5)
RNA-seq of total RNA (4)
RNA-seq of coding RNA from single cells (3)
RNA-seq of non coding RNA (3)
Human - High-throughput sequencing (2)
Animal - Single-cell sequencing (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
Spatial transcriptomics by high-throughput sequencing (1)
Other (1)
MicroRNA profiling by array (1)
Methylation profiling by array (1)

Release Date

2022 (556)
2021 (521)
2023 (514)
2025 (422)
2020 (404)
2024 (360)
2018 (315)
2019 (309)
2017 (297)
2016 (267)
2015 (240)
2014 (199)
2013 (143)
2011 (142)
2012 (139)
2010 (124)
2008 (75)
2009 (72)
2026 (52)
2007 (50)
2006 (33)
2004 (17)
2005 (17)
2003 (9)
2001 (6)
2002 (5)
2000 (5)
1998 (1)
1997 (1)

Lab affiliation

University of Alabama at Birmingham, O'Neal Mass Spectrometry Proteomics Shared Facility (4)
The University of Melbourne (4)
Research Unit for Molecular Medicine, Department of Clinical Medicine, Aarhus University, Denmark (3)
iBiMED – Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Aveiro, Portugal; UnIC – Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal (2)
King's British Heart Foundation Centre, King's College London, UK (2)
University Medical Center Goettingen, Department of Clinical Chemistry, Core Facility Proteomics (2)
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China (1)
Translational Biology and Engineering Program, Ted Rogers Centre for Heart Research, Toronto, Ontario M5G 1M1, Canada (1)
Instituto de Investigacion Biomediaca de A Coruna (INIBIC) - Complexo Hospitalario Universitario de A Coruna, A Coruna, SPAIN (1)
Ultrasound Department, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine (1)
SBBS, Conway Institute, UCD, Belfield, Dublin (1)
Charles Perkins Centre and School of Medical Sciences, University of Sydney, Australia (1)
Department of Experimental Pharmacology and 35 Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 36 Martinistrasse 52, 20246 Hamburg, Germany (1)
State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China. (1)
Biomedical Engineering Department Oregon Health & Science University Portland, OR 97239 (1)
Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany (1)
1.Semmelweis University, Department of Pharmacology and Pharmacotherapy, Budapest, Hungary. 2.Pharmahungary Group, Szeged, Hungary (1)
Lelie Dan Faulty of Pharmacy, Univerity of Toronto (1)
Laboratory for Functional Genome Analysis, Gene Center, LMU Munich, 81377 Munich, Germany (1)
Department of Forensic Medicine, Faculty of Basic Medical Sciences, Chongqing Medical University (1)
Agnes Ginges Centre for Molecular Cardiology (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (1)
University of Toronto Translational Biology and Engineering Program, Ted Rogers Centre for Heart Research (1)
Kelly: Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida, USA. Coon: Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA Genome Center, University of Wisconsin-Madison, Madison, WI 53706, USA (1)
Director, CSIR-INDIAN INSTITUTE OF CHEMICAL BIOLOGY, KOLKATA,INDIA (1)
Chair of Pathological Physiology, Institute of Bio- and Translational Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia (1)
Biomedical Research Centre, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic (1)
Pharmaceutical Sciences - TTB Roche Pharma Research and Early Development Roche Innovation Center Basel F. Hoffmann-La Roche Ltd Building/Room 93/4.44 Grenzacherstrasse 124 CH-4070 Basel, Switzerland (1)
Institute of Cellular Biology and Pathology "N. Simionescu", Proteomics Department, Bucharest, Romania (1)
Department of Internal Medicine, Botucatu Medical School, São Paulo State University, UNESP, SP, Brazil (1)

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Untargeted Metabolomic Profiling of Left Ventricular Myocardium in a Mouse Model of Diabetic Cardiomyopathy

This study characterizes metabolic alterations in the left ventricular myocardium of a high-fat diet and streptozotocin-induced mouse model of diabetic cardiomyopathy. Untargeted LC–MS/MS metabolomics was performed using a Vanquish UHPLC system coupled to an Orbitrap Exploris 120 mass spectrometer. ...

2026-07-20 | MTBLS15043 | MetaboLights

Deletion of Gja1 in myocardium emerges ventricular arrhythmia and tachycardia by reprogramming proline metabolism

Connexin43 (Cx43) is the predominant connexin in working myocardium. Its expression decreases in various cardiovascular diseases, and accompanied by ventricular arrhythmias (VAs). However, molecular mechanisms underlying increased arrhythmogenesis remained unclear. Here we established iPSC-derived c...

2025-11-11 | MTBLS13302 | MetaboLights

Noncoding RNA expression in myocardium from infants with tetralogy of Fallot

This SuperSeries is composed of the following subset Series: GSE35490: Noncoding RNA expression in myocardium from infants with tetralogy of Fallot [miRNA profiling] GSE35776: Noncoding RNA expression in myocardium from infants with tetralogy of Fallot [mRNA profiling] Refer to individual Series

ORGANISM(S): Homo sapiens

2012-07-11 | E-GEOD-35781 | biostudies-arrayexpress

Noncoding RNA expression in myocardium from infants with tetralogy of Fallot [miRNA profiling]

This is the first report characterizing noncoding RNA expression in a congenital heart defect. The striking shift in expression of noncoding RNAs reflects a fundamental change in cell biology, likely impacting expression, transcript splicing and translation of developmentally important genes and pos...

ORGANISM(S): Homo sapiens

2012-07-11 | E-GEOD-35490 | biostudies-arrayexpress

Transcription profiling of human heart tissue: hibernating versus normal myocardium

Title: Gene expression profiling of human heart samples: a comparison between normal and hibernating myocardium.
Description: The aim of this project is to investigate the changes in global gene
expression in hibernating,(preserved wall thickness, impaired
contractility at re...

ORGANISM(S): Homo sapiens

2006-12-31 | E-MIMR-27 | biostudies-arrayexpress

Phosphoproteomic analysis of neonatal regenerative myocardium revealed important roles of CHK1 via activating mTORC1/P70S6K pathway

Restoring the regenerative capacity of myocardium, which presents shortly in the newborns but lost in adulthood, is one of the therapeutic options for myocardial repair post various insults. In this work, we performed the phosphoproteomic analysis on neonatal regenerative myocardium and explored the...

ORGANISM(S): Mus musculus (Mouse)

2020-02-28 | PXD014865 | Pride

Transcription profiling of human atrial and ventricular myocardium from patients atrial tissue of patients with sinus rhythm vs. human left ventricular non-failing myocardium to identify the transcriptional basis for ultrastructural and functional specialization of human atria and ventricles

Note this data set has identical data files: Files GSM40994.txt and GSM40995.txt. GSE2240 contains two different experimental subsets:; 1) Comparison of atrial and ventricular gene expression (atrial tissue of patients with sinus rhythm vs. human left ventricular non-failing myocardium); The purpose...

ORGANISM(S): Homo sapiens

2007-10-27 | E-GEOD-2240 | biostudies-arrayexpress

Deregulation of miRNAs in Infant Outflow Tract Myocardium of Non-syndromic Tetralogy of Fallot

Tetralogy of Fallot (TOF) is one of the most common heart defects in children and the underlying mechanisms remain elusive. miRNAs are a recently discovered class of regulators of gene expression and are becoming increasingly recognized as important regulators of heart development and function. The ...

ORGANISM(S): Homo sapiens

2012-08-14 | E-GEOD-40128 | biostudies-arrayexpress

Age-independent Cardiac Protection by Pharmacological Activation of Beclin-1 During Endotoxemia and Its Association with Energy Metabolic Reprograming in Myocardium — A Targeted Metabolomics Study

Not available

ORGANISM(S): Mus musculus

ST002178 | MetabolomicsWorkbench

Transcription profiling by array and functional characterization of developing cardiomyocytes from recombinant murine embryonic stem cells

Here, we characterize the transcriptome of the mouse embryonic stem cell line CM7-1 during differentiation into beating cardiomyocytes and compared the gene expression profiles with those from primary adult murine cardiomyocytes and left ventricular myocardium.

ORGANISM(S): Mus musculus

2009-03-21 | E-MEXP-1405 | biostudies-arrayexpress

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