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MetabolomicsInvestigating the Mechanisms of Silver Nanoparticle Toxicity in Daphnia magna: A Multi-Omics Approach
Silver nanoparticles (AgNPs), one of the most common nanomaterials in use today, have been shown to enter the aquatic environment from use of commercially obtained products. Although acute toxicity has been shown in vitro and in vivo, there is still a great deal of uncertainty surrounding the molecu...
2017-05-08 | MTBLS260 | MetaboLights
ProteomicsSilver binding proteins in S. aureus
The rapid emergence of drug resistant Staphylococcus aureus (S. aureus), in particular, methicillin-resistant S. aureus (MRSA) poses a serious threat to public health globally. Reuse of metal-based antimicrobials stands for one of the most promising strategies to resensitize drug resistant bacteria ...
ORGANISM(S): Staphylococcus aureus 
2021-09-10 | PXD025106 | Pride
Silver-binding protein S. aureus 
MetabolomicsComparative LC/MS-based profiling of silver nitrate-treated Arabidopsis thaliana leaves of wild-type and cyp79B2 cyp79B3 double knockout plants
Indole-3-acetaldoxime (IAOx) represents an early intermediate of the biosynthesis of a variety of indolic secondary metabolites including the phytoanticipin indol-3-ylmethyl glucosinolate and the phytoalexin camalexin (3-thiazol-2′-yl-indole). Arabidopsis thaliana cyp79B2 cyp79B3 double knockout pla...
2012-05-22 | MTBLS2 | MetaboLights
TranscriptomicsGenomewide methylation analysis in Silver Russell syndrome patients
Genomewide methylation analysis in Silver Russell syndrome patients compared to healthy controls Bisulphite converted DNA from the 24 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip
ORGANISM(S): Homo sapiens 
2015-01-12 | E-GEOD-55491 | biostudies-arrayexpress
TranscriptomicsCharacterization and comparative profiling of microRNA transcriptomes in bighead carp and silver carp
We applied high throughput sequencing technology to identify microRNA genes in bighead carp and silver carp. We identified 167 conserved miRNAs in bighead carp and 166 in silver carp. By two computational stragegies, we obtained 39 novel miRNAs in bighead carp and 54 in silver carp, for which, no ho...
ORGANISM(S): Hypophthalmichthys nobilis 
2010-09-01 | E-GEOD-22232 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiles of zebrafish embryos exposed to silver (nanoparticles, bulk and ions) using HT-SuperSAGE in a Illumina GA2 platform
Silver nanoparticles cause toxicity in exposed organisms and are an environmental health concern. The mechanisms of silver nanoparticle toxicity, however, remain unclear. We examined the effects of exposure to silver in nano-, bulk- and ionic forms on zebrafish embryos (Danio rerio) using a Next Gen...
ORGANISM(S): Danio rerio 
2013-06-17 | E-GEOD-38125 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of silver fox brain selected for tame behavior vs non-selected silver fox
Comparison of brain gene expression between silver foxes selected for tame behavior and non-selected silver fox.
ORGANISM(S): Vulpes vulpes 
2005-12-31 | E-MEXP-451 | biostudies-arrayexpress
TranscriptomicsMechanisms of response to silver nanoparticles Enchytraeus albidus (Oligochaeta): survival, reproduction and gene expression profile
Due to its antimicrobial activity, silver nanoparticles (Ag-NPs) are among the most used NPs worldwide, yet little information is available regarding their effects, particularly in soil dwelling organisms. Enchytraeids (Oligochaeta) are important members of the soil fauna which actively contribute t...
ORGANISM(S): Enchytraeus albidus 
2013-05-22 | E-GEOD-42431 | biostudies-arrayexpress
TranscriptomicsTranscription profiling twenty eight growth restricted patients (including twenty two with Silver-Russel syndrome) and their parents
We studied twenty-eight growth restricted patients (twenty-two with Silver-Russell syndrome, OMIM#180860) and their parents with the Affymetrix 250K Sty SNP microarray. All patients were molecularly undefined, and thus the aim was to look for copy number alterations that might contribute to the grow...
ORGANISM(S): Homo sapiens 
2009-09-06 | E-MTAB-56 | biostudies-arrayexpress
TranscriptomicsChanges in Arabidopsis thaliana gene expression in response to silver nanoparticles and silver ions
The release of silver nanoparticles (SNPs) in the environment has raised concerns about their effects on living organisms, including plants. In this study, changes in gene expression in Arabidopsis thaliana exposed to SNPs and silver ions (Ag+) were analyzed using Affymetrix expression microarrays. ...
ORGANISM(S): Arabidopsis thaliana 
2014-02-12 | E-MEXP-3950 | biostudies-arrayexpress
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