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TranscriptomicsMouse hybrid sterility X2 (Hstx2) controls meiotic asynapsis of heterosubspecific homologs and probes into the dominance theory of Haldane's rule.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-49462 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling of isolated populations of prepachytene spermatocytes, pachytene spermatocytes and spermatids of PWD and B6 male mice
MiRNA expression profiling of isolated populations of prepachytene spermatocytes (LP), pachytene spermatocytes (RP) and spermatids (ST) from PWD and B6 was performed to study the genome wide variation in miRNA expression between two mouse subspecies. Populations of pre-pachytene spermatocytes, pachy...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-49443 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in testis of mouse inter-subspecific hybrids
MiRNA expression profiling on 14.5 day old testis from sterile (PWD x B6)F1, (PWK x B6)F1 and fertile (B6 x PWD)F1 inter-subspecific hybrids were performed to study the genome wide variation in miRNA expression between different inter-subspecific hybrids during meiosis. The total RNA (120 ng) sample...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-49442 | biostudies-arrayexpress
TranscriptomicsExpression profiles in testis of mouse inter-subspecific hybrids
According to Dobzhansky-Muller model, hybrid sterility is a consequence of independent evolution of related taxa resulting in incompatible interaction during gametogenesis of their hybrids. We proposed that asynapsis of heterospecific chromosomes in meiotic prophase provides a general and recurrentl...
ORGANISM(S): Mus musculus 
2012-11-07 | E-GEOD-41707 | biostudies-arrayexpress
TranscriptomicsExpression profiling of isolated populations of prepachytene spermatocytes, pachytene spermatocytes and spermatids of PWD and B6 males
Expression profiling of isolated populations of prepachytene spermatocytes (LP), pachytene spermatocytes (RP) and spermatids (ST) from PWD and B6 was performed to study the genome wide variation in gene expression between two mouse subspecies. To evaluate the transcriptional difference between B6 an...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-49444 | biostudies-arrayexpress
Proteomics,MultiomicsDefining the effects of genetic variation on a proteome-wide scale
Genetic variation governs protein expression through both transcriptional and post-transcriptional processes. To investigate this relationship, we combined a multiplexed, mass spectrometry-based method for protein quantification with an emerging mouse model harboring extensive genetic variation fro...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-11-08 | MSV000081696 | MassIVE
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