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TranscriptomicsEffect of deferasirox and deferoxamine treatment on hematopoietic stem cells gene expression
To investigate new molecular pathways affected by deferasirox or deferoxamine able to explain hematopoiesis restoration
ORGANISM(S): Homo sapiens 
2019-09-02 | E-MTAB-6658 | biostudies-arrayexpress
TranscriptomicsGene expression profile of normal thyroid tissue as indicator of thyroid carcinoma during thyroidectomy
In the present study, we examine expression profiles of normal tissue fragments, intraoperatively taken on the basis of macroscopic judgment and confirmed by immunohistochemistry, from patients with neoplastic and non-neoplastic disease of thyroid. The distinct GEP detected may influence the insurge...
ORGANISM(S): Homo sapiens 
2016-05-06 | E-MTAB-3796 | biostudies-arrayexpress
TranscriptomicsOvarian cancer cell lines PEA1 in low glucose condition shows metabolism-driven inflammation
Transcription profiling by array of PEA1 cell lines in low glucose growth condition compared to normal growth condition
ORGANISM(S): Homo sapiens 
2016-05-25 | E-MTAB-3799 | biostudies-arrayexpress
TranscriptomicsComparative gene expression profiling of tobacco-associated HPV-positive versus negative oral squamous carcinoma cell lines
HPV-positive oral squamous cell carcinomas (OSCCs) are specific biological and clinical entities, characterized by a more favorable prognosis compared to HPV-negative OSCCs and occurring generally in non-smoking and non-drinking younger individuals. However, poor information is available on the mole...
ORGANISM(S): Homo sapiens 
2019-12-01 | E-MTAB-6152 | biostudies-arrayexpress
TranscriptomicsmiRNA analysis revealed regulatory networks in gastrointestinal stromal tumors (GIST)
A growing body of literature has consolidated the important role of miRNA in a variety of biological processes, in cancer development, acting both as oncogenes and tumor suppressor genes, and in their ability to distinguish tumors according to their diagnostic and prognostic properties.To date, litt...
ORGANISM(S): Homo sapiens 
2016-10-03 | E-MTAB-4490 | biostudies-arrayexpress
TranscriptomicsTRAP1 gene silencing in MCF7 cell lines
Transcription profiling by array of MCF7 cell lines silenced with TRAP1 small interfering RNA compared with scramble
ORGANISM(S): Homo sapiens 
2017-06-30 | E-MTAB-3584 | biostudies-arrayexpress
TranscriptomicsTRAP1 silencing in HCT116 cells
Trascription profiling analysis was performed on HCT-116 cell lines transiently silenced with TRAP1 compared with scrumble
ORGANISM(S): Homo sapiens 
2014-11-15 | E-MTAB-2500 | biostudies-arrayexpress
TranscriptomicsEphA3 is a novel molecular target in Multiple Myeloma
EphA3-mRNA silencing significantly inhibited the ability of MM PCs to adhere to fibronectin, to stromal cells and to invade in vitro, without affecting proliferation or viability. Gene expression profiling showed that knockdown of EphA3 modulated some molecules that regulate adhesion, migration and ...
ORGANISM(S): Homo sapiens 
2017-06-30 | E-MTAB-4265 | biostudies-arrayexpress
UnknownHigh-density neutrophils in MGUS and multiple myeloma are dysfunctional and immune-suppressive due to increased STAT3 downstream signaling.
Not available
S-EPMC7005058 | biostudies-literature
UnknownPredicting poor peripheral blood stem cell collection in patients with multiple myeloma receiving pre-transplant induction therapy with novel agents and mobilized with cyclophosphamide plus granulocyte-colony stimulating factor: results from a Gruppo Italiano Malattie EMatologiche dell'Adulto Multiple Myeloma Working Party study.
Not available
S-EPMC4425876 | biostudies-literature
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