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MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
UnknownIntensive Aerobic Cycling Is Feasible and Elicits Improvements in Gait Velocity in Individuals With Multiple Sclerosis: A Preliminary Study.
Not available
S-EPMC11096857 | biostudies-literature
ProteomicsLabel-free shotgun proteomics analysis in zebrafish liver following dietary exposure to the pesticide dieldrin
The objective of this study was to determine the effect of dieldrin on the hepatic proteome in the zebrafish liver following dietary exposure. Female zebrafish were fed a control dose or one of three doses of DLD-contaminated food pellets over 21 days.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2019-08-29 | PXD014480 | Pride
Liver Zebrafish Lc-ms/ms 
UnknownGut microbiota composition and relapse risk in pediatric MS: A pilot study.
Not available
S-EPMC4806409 | biostudies-literature
UnknownPharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.
Not available
S-EPMC6312637 | biostudies-literature
ProteomicsAdvanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) hold tremendous promise for in vitro modeling 2 to assess native myocardial function and disease mechanisms as well as testing drug safety and efficacy. However, 3 current iPSC-CMs are functionally immature, resembling in vivo CMs of fe...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD036639 | Pride
Electrophysiology Metabolism Contractility Proteomics Screening Myocardium Tissue engineering Rna sequencing 
MetabolomicsMetabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

Breast cancer metastasis occurs via blood and lymphatic vessels. Breast cancer cells 'educate' lymphatic endothelial cells (LECs) to support tumor vascularization and growth. However, despite known metabolic alterations in breast cancer, it remains unclear how lymphatic endothelial cell metabolis...

2024-06-25 | MTBLS859 | MetaboLights
UnknownGenetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.
Not available
S-EPMC3894577 | biostudies-literature
ProteomicsMulti-omic profiling of early pregnancy small and large plasma extracellular vesicles reveals placental, metabolic, and structural adaptation signatures
Early human pregnancy is a critical period characterized by rapid growth and extensive maternal-fetal communication that influence both maternal and fetal outcomes. Circulating extracellular vesicles (EVs) have the capacity to capture cargo that reflect these processes in real-time; however, signatu...
ORGANISM(S): Homo sapiens (Human) 
2026-10-05 | PXD074792 | Pride
Pregnancy Maternal-fetal communication Proteomics Extracellular vesicles Mitochondria Transcriptomics Placenta 
UnknownGlycoproteomic analysis identifies human glycoproteins secreted from HIV latently infected T cells and reveals their presence in HIV+ plasma.
Not available
S-EPMC4015807 | biostudies-literature
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