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TranscriptomicsMycobacterium tuberculosis efpA CRISPRi knock-down transcriptional profile - induced efpA knock-down strain vs non-induced condition
In Mycobacterium tuberculosis, the efflux pump, EfpA, plays an essential but uncharacterised role in its physiology and antibiotic tolerance. In this study, an ATc-inducible CRISPR interference (CRISPRi) system was introduced into M. tuberculosis to knock-down the expression of efpA and determine an...
ORGANISM(S): Mycobacterium tuberculosis 
2024-06-19 | E-MTAB-13755 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of renal cancer from the Cancer Genomics of the Kidney (CAGEKID) project
The incidence of renal cell carcinoma (RCC) is increasing worldwide, and its prevalence is particularly high in some parts of Central Europe. The study describes transcriptome sequencing of clear cell RCC (ccRCC), the most common form of the disease, in patients from four different European countri...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-MTAB-3033 | biostudies-arrayexpress
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