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PGE2 is a major mediator of inflammation and is present at high concentrations in the synovial fluid of rheumatoid arthritis (RA) patients. PGE2, acting through the EP4 receptor, has both pro- and anti-inflammatory roles in vivo. To shed light on this dual role of PGE2, we investigated its effects ...
ORGANISM(S): Homo sapiens 
Mutational landscapes of primary triple negative breast cancers - WGS
Mutational landscapes of primary triple negative breast cancers - RNA seq
tumour samples using Affymetrix Genome-Wide SNP6.0 arrays
Mutational landscapes of primary triple negative breast cancers - Exomes
Primary triple negative breast cancers (TNBC) represent approximately 16% of all breast cancers and are a tumour type defined by exclusion,for which comprehensive landscapes of somatic mutation have not been determined. Here we show in 104 early TNBC cases, that at the time of diagnosis these cancer...
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