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TranscriptomicsMicroarray analysis of the NK92MI cell line treated with CD200 peptide at 2hr and 4hr timepoints compared to untreated
We used RNA microarray to investigate CD200-mediated apoptosis on the NK92MI celll line. We aimed to identify apoptotic gene signatures. RNA was extracted from NK92MI cells and sent for sequencing. raw sequencing data was then processed in R using 'lumi' and 'limma' packages.
ORGANISM(S): Homo sapiens 
2022-08-25 | E-MTAB-12035 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of primary human basal cell carcinoma, squamous cell carcinoma, and normal skin
We used RNA microarray to investigate the expression of full-time and part-time sheddases and their substrates in basal cell carcinoma when compared to squamous cell carcinoma and normal skin. We aimed to identify the involvement of these sheddases in CD200 ectodomain shedding. RNA was extracted fro...
ORGANISM(S): Homo sapiens 
2022-08-25 | E-MTAB-12034 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of SDH-deficient immortalized kidney epithelial cells
Succinate dehydrogenase (SDH) is a mitochondrial protein complex responsible for the oxidation of succinate to fumarate in the tricarboxylic acid cycle. Loss-of-function mutations in any of the SDH genes are associated with susceptibility to develop neu-roendrocrine neoplasms and renal cell carcinom...
ORGANISM(S): Mus musculus 
2016-01-22 | E-MTAB-4349 | biostudies-arrayexpress
TranscriptomicsEimeria falciformis infection of the mouse caecum identifies opposing roles of IFNg-regulated host pathways for the parasite development
Intracellular parasites reprogram the host functions for their survival and reproduction. Conversely, the infected host attempts to defend the microbial insult. The extent and relevance of parasite-mediated host response in vivo remains poorly studied. We utilized Eimeria falciformis, an obligate in...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-49948 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human cell line HepG2 edited with CRISPR and treated with splice-switching oligo inhibiting a pseudoexon in PCCA against control SSO and control HepG2 cells
Cellular models of propionic acidemia were generated using HepG2 cells that were edited by CRISPR gene editing to introduce the pathogenic PCCA c.1285-1416A>G variant associated with propionic acidemia, and a 7 bp deletion of a predicted hnRNP A1 binding motif (c.1285-1411delTAGAACA), which causes c...
ORGANISM(S): Homo sapiens 
2023-12-10 | E-MTAB-13549 | biostudies-arrayexpress
UnknownWhen generative artificial intelligence answers to Google Trends about spondyloarthritis: what does a French expert panel think about it?
Not available
S-EPMC12278117 | biostudies-literature
UnknownNational randomized controlled trial of virtual house calls for Parkinson disease.
Not available
S-EPMC5595275 | biostudies-literature
TranscriptomicsCultured human adipose tissue pericytes and mesenchymal stromal cells display a very similar gene expression profile
Mesenchymal stromal cells (MSCs) are cultured cells that can give rise to mature mesenchymal cells under appropriate conditions, and secrete a number of biologically relevant molecules that may play an important role in regenerative medicine. Evidence indicates that pericytes (PCs) correspond to mes...
ORGANISM(S): Homo sapiens 
2015-07-22 | E-GEOD-67747 | biostudies-arrayexpress
TranscriptomicsMajor Depressive Disorder blood gene expression
Background: Major Depressive Disorder (MDD) is a moderately heritable disorder with a high lifetime prevalence. At present, laboratory blood tests to support MDD diagnosis are not available. Methods: We used a classifier approach on blood gene expression profiles of a unique set of non-medicated su...
ORGANISM(S): Homo sapiens 
2011-10-04 | E-GEOD-19738 | biostudies-arrayexpress
GenomicsIgA Nephropathy GWAS (IGANGWAS)

We report a genome-wide association study of IgA nephropathy, a main cause of kidney failure. All subjects were of Chinese Han ancestry, of which 1,194 were cases and 902 controls. Genomic DNA samples extracted from whole blood were genotyped on the Illumina 610 Quad platform.

phs000431.v1.p1 | EGA
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