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TranscriptomicsCrosstalk between the STAT3, NF-kB and Notch signaling pathways in glioblastoma stem cells
In this study, we describe a novel relationship between glioblastoma CSCs and the Notch pathway, which involves the constitutive activation of STAT3 and NF-κB signaling. We demonstrate that adherent glioma CSCs exhibit characteristics previously described for CSCs grown in suspension culture. The ex...
ORGANISM(S): Homo sapiens 
2013-06-19 | E-GEOD-48079 | biostudies-arrayexpress
TranscriptomicsIdentification and molecular characterization of distinct glioblastoma cancer stem cell populations
Malignant glioblastoma (GBM) is a highly aggressive brain tumor with a dismal prognosis and limited therapeutic options. Genomic profiling of GBM samples in the TCGA database has identified four molecular subtypes (Proneural, Neural, Classical and Mesenchymal), which may arise from different gliobla...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-65576 | biostudies-arrayexpress
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
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