Sort   by:  
 Page size 
ProteomicsTD-MS analysis of single-domain antibody and anti-EGFR single-domain antibody-drug conjugate
Analysis of the intact single-domain antibody and its associated anti-EGFR single-domain antibody-drug conjugate. Optimizations of conditions with various fragmentation methods.
ORGANISM(S): Cellular Organisms 
2025-02-11 | PXD058380 | JPOST Repository
UnknownIsolation of rabbit single domain antibodies to B7-H3 via protein immunization and phage display.
Not available
S-EPMC7052794 | biostudies-literature
UnknownAncient species offers contemporary therapeutics: an update on shark VNAR single domain antibody sequences, phage libraries and potential clinical applications.
Not available
S-EPMC7034638 | biostudies-literature
TranscriptomicsTranscription profiling by array of human SK-N-AS neuroblastoma xenograft tumor treated with anti-human IGF-IR monoclonal antibody (h10H5) to study the anti-tumour function of the antibody
The insulin-like growth factor (IGF) system consists of two ligands (IGF-I and IGF-II), which both signal through type I IGF receptor (IGF-IR) to stimulate proliferation and inhibit apoptosis, with activity contributing to malignant growth of many types of human cancers. We have developed a humanize...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11959 | biostudies-arrayexpress
UnknownEngineering a novel light-chain single-domain antibody to enable IgG-format bispecific antibody design.
Not available
S-EPMC12598741 | biostudies-literature
TranscriptomicsSingle cell RNA sequencing of stem cell-derived retinal ganglion cells
We used human embryonic stem cell-derived retinal ganglion cells (RGCs) to characterize the transcriptome of 1,174 cells at the single cell level. The human embryonic stem cell line BRN3B-mCherry A81-H7 was differentiated to RGCs using a guided differentiation approach. Cells were harvested at day 3...
ORGANISM(S): Homo sapiens 
2017-10-07 | E-MTAB-6108 | biostudies-arrayexpress
ProteomicsAntibody RING-Mediated Destruction (ARMeD) of endogenous proteins
To help understand the cellular function of a gene the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein product of the gene, which is either permanently abrogated or depleted at a rate defined by th...
ORGANISM(S): Homo Sapiens 
2020-05-28 | PXD016193 | panorama
ProteomicsRobust collection and processing for label-free single voxel proteomics
With advanced mass spectrometry (MS)-based proteomics, genome-scale proteome coverage can be achieved from bulk tissues. However, such bulk measurement lacks spatial resolution and obscures important tissue heterogeneity, which make it impossible for proteome mapping of tissue microenvironment. Here...
ORGANISM(S): Homo Sapiens (human) 
2024-11-01 | PXD045043 | JPOST Repository
ProteomicsProteomic identification of the proteins that co-precipitated with FUT8
Essential roles of FUT8 SH3 domain in core fucosylation
ORGANISM(S): Homo Sapiens (human) 
2020-04-29 | PXD018032 | JPOST Repository
TranscriptomicsGlobal Deterministic and Stochastic Allelic Specific Gene Expression in Single Blastomeres of Mouse Early Embryos
Here we modified a single cell whole transcriptome amplification method to make it capable of amplifying cDNAs as long as 3kb efficiently and unbiasedly. We combined this modified single cell cDNA amplification method with Applied Biosystems next generation sequencing SOLiD™ System to set up a singl...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-22182 | biostudies-arrayexpress
Sort   by:  
 Page size