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Proteomicsthe proteomic profiles of single-sex infected female worms and bisexual infected mature female worms of Schistosoma japonicum at 18, 21, 23 and 25 days post infection
Revealing the reproductive mechanism of schistosomes will help to control this disease. In this study, the proteomic profiles of single-sex infected female (SF) worms and bisexual infected mature female (MF) worms of Schistosoma japonicum at 18, 21, 23 and 25 days post infection (dpi) were identifie...
ORGANISM(S): Schistosoma japonicum (Blood fluke) 
2024-01-26 | PXD030834 | Pride
Lc-ms/ms Itraq Bisexual infected mature female Schistosoma japonicum Single-sex infected female 
TranscriptomicsSingle cell RNA Sequencing (scRNA-Seq) on human embryonic stem cell-derived thyroid organoids exposed for 3 days to sex hormones + 1 day to benzo[a]pyrene (BaP) or PCB153
Human embryonic stem cell-derived thyroid follicles were exposed for 3 days to a mixture of the sex hormones beta-estradiol (E2), 5-alpha-dihydrotestosterone (DHT) and progesterone (PG) that resemble the serum levels of human male and female (post-ovulation) of reproductive age. Afterwards, they wer...
ORGANISM(S): Homo sapiens 
2024-08-29 | E-MTAB-13502 | biostudies-arrayexpress
ProteomicsComparative proteomic profiles of Schistosoma japonicum male worms derived from single-sex and bisexual infections
Schistosomiasis, which is caused by parasitic schistosomes, remains the second most prevalent parasitic disease of mammals worldwide. To successfully maintain fecundity, schistosomes have evolved a lifecycle that involves the cooperation of morphologically distinct male and female forms. Eggs produc...
ORGANISM(S): Schistosoma Japonicum 
2022-11-11 | PXD038091 |
TranscriptomicsTranscription profiling of Bi-sex male and female Schistosoma mansoni worms isolated from mice 7-weeks post-infection
Bi-sex male and female Schistosoma mansoni worms were isolated from mice 7-weeks post-infection. Bi-sex male material or female material was compared in a direct bimodal comparison to single-sex male or female material. Two independent biological batches of both bi- and single-sex males were used. ...
ORGANISM(S): Schistosoma mansoni 
2006-11-01 | E-MEXP-474 | biostudies-arrayexpress
ProteomicsComparative proteome analysis of the tegument of male and female adult Schistosoma mansoni
We present a comparative analysis of sex-specific tegument proteins of paired or virgin Schistosoma mansoni. By apply a new and highly sensitive workflow, detection of even low abundance proteins from the worm was achieved Therefore, a streptavidin-biotin affinity purification technique in combinati...
ORGANISM(S): Schistosoma mansoni (Blood fluke) 
2022-05-20 | PXD031167 | Pride
Schistosoma manson Proteome Tegument 
TranscriptomicsThe Sex-Specific Changes in Gene Expression and Behavior Induced by Chronic Toxoplasma Infection in Mice
The goal of this study was to identify the neural systems that underlie the behavorial changes in intermediate hosts of Toxoplasma gondii. Using a mouse whole genome microarray, we analyzed gene expression in the frontal cortex during the latent stages of infection. We found marked sex-dependent e...
ORGANISM(S): Mus musculus 
2014-07-28 | E-GEOD-31207 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of female Schistosoma mansoni from an unisexual infection of mice compared to worms from a mixed sex infection
In this study we describe the use of DNA microarrays to study the effect of sexual pairing of Schistosoma mansoni in the female gene expression. To accomplish this objective we compared female worms from unisexual infection with worms from mixed sex infection.
ORGANISM(S): Schistosoma mansoni 
2007-06-26 | E-MEXP-805 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Schistosoma mansoni cercariae using genomic DNA as an indirect reference for identifying gender associated transcripts in morphologically identical but chromosomally distinct cercariae
Use of genomic DNA as an indirect reference for identifying gender associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae
ORGANISM(S): Schistosoma mansoni 
2008-10-01 | E-MEXP-1259 | biostudies-arrayexpress
TranscriptomicsEstrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors
E2 exposure significantly decreased peak viral titer in hNECs from female donors. We used microarray analyses to identify global gene expression patterns between E2 and vehicle exposed hNECs from female donors Influenza causes an acute infection characterized by virus replication in respiratory epit...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-75208 | biostudies-arrayexpress
ProteomicsThe production of Excretory-Secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures.
In this study, the composition of ES of male and female L4 stage Heligmosomoides polygyrus bakeri in the presence (cultured together) or absence (cultured alone) of the opposite sex was examined using mass spectrometry.
ORGANISM(S): Heligmosomoides polygyrus bakeri 
2021-09-10 | PXD023759 | Pride
Lc-ms/ms Nematode Heligmosomoides polygyrus bakeri Excretory-secretory products 
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