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We investigated chromosomal imbalances in samples from patients with androgen insensitive prostate cancer. 4 archival FFPE tumor samples were analyzed with Affymetrix 250K Nsp SNP microarrays and virtual-karyotype results for PTEN region were compared to PTEN deletion analysis by FISH.
ORGANISM(S): Homo sapiens 
The biphasic epithelioid (E-) and sarcomatoid(S-) components of sarcomatoid RCC and epithelioid (E-) and rhabdoid (R-) components of rhabdoid RCC shared a similar transcriptomic signature, despite morphologic differences; by contrast, the transcriptome of sarcomatoid and rhabdoid RCC was sharply dis...
ORGANISM(S): Homo sapiens 
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