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MetabolomicsInositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites
Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of membrane tethers to contact sites between the endoplasmic reticulum (ER) and the plasma membrane is often triggered by calcium. In contrast, we reveal here a funct...
2021-05-06 | MTBLS2444 | MetaboLights
MetabolomicsA paired transcriptomic, metabolomic and fruit-quality data resource from field-grown tomatoes across eight agricultural sites in Ningxia, China

Tomato fruit phenotypes are shaped by genotype, agronomic management and local environment, yet matched molecular and environmental datasets from commercial field settings remain scarce. Here we describe a paired resource comprising fruit transcriptomes, untargeted metabolomes, fruit-quality meas...

2026-09-14 | MTBLS15436 | MetaboLights
MetabolomicsLipidomics study of different fat deposition sites in wuzhishan pigs with double knockout of APOE/LDLR
Apolipoprotein E (APOE) and the low-density lipoprotein receptor (LDLR) play a key role in regulating lipoprotein transport and cholesterol homeostasis. However, their roles in porcine fat deposition and adipose tissue remodelling are not well understood. This study utilised wild-type (WT) and APOE/...
2026-09-09 | MTBLS15330 | MetaboLights
MetabolomicsMap of microbially induced metabolic changes across diverse body sites in mice - Mouse Data
Not available
ORGANISM(S): Mus musculus 
ST002465 | MetabolomicsWorkbench
MetabolomicsMap of microbially induced metabolic changes across diverse body sites in mice - Bacterial culture data
Not available
ORGANISM(S): Several mouse commensals 
ST002289 | MetabolomicsWorkbench
GenomicsThe Genomic Binding Sites of an Endogenous Non-Coding RNA
Long non-coding RNAs (lncRNAs) have important regulatory roles and can function at the level of chromatin. To determine where lncRNAs bind to chromatin, we developed CHART, a hybridization-based technique that specifically enriches endogenous RNAs along with their targets from reversibly-crosslinked...
ORGANISM(S): Drosophila melanogaster 
2011-12-07 | E-GEOD-28180 | biostudies-arrayexpress
GenomicsIdentification and Characterization of Hoxa9 Binding Sites in Hematopoietic Cells
The clustered homeobox proteins play crucial roles in development, hematopoiesis and leukemia yet the targets they regulate and their mechanisms of action are poorly understood. Here, we identified the binding sites for Hoxa9 and the Hox cofactor Meis1 on a genome-wide level and profiled their asso...
ORGANISM(S): Mus musculus 
2011-12-04 | E-GEOD-33509 | biostudies-arrayexpress
TranscriptomicsIdentification of SRF binding sites in Three Human Cell types
We used chromatin immunoprecipitation (ChIP) in combination with human promoter microarrays to identify 216 putative SRF binding sites in the human genome. We performed independent quantitative PCR validation at over half of these sites that resulted in 146 sites we assert to be true binding sites ...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-5998 | biostudies-arrayexpress
TranscriptomicsMYC binding sites in HeLa cells
MYC binding sites determined in HeLa cells using ChIP-chip ChIP-chip
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4354 | biostudies-arrayexpress
TranscriptomicsRibonuclease L and Metal-Ion-Independent Endoribonuclease Cleavage Sites in Host and Viral RNAs
We used 2', 3'-cyclic phosphate cDNA synthesis and Illumina sequencing to identify and quantify metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. To make cDNA libraries, we exploited the 2’, 3’-cyclic phosphate at the end of RNA fragments produced by RNase L and other met...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-52489 | biostudies-arrayexpress
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