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ProteomicsThe Importance of Extracellular Vesicle Purification for Downstream Analysis: A Comparison of Differential Centrifugation and Size Exclusion Chromatography for Parasitic Helminths
Fascioliasis is a major neglected tropical disease that infects humans and ruminant species worldwide. Recent discoveries have identified that liver fluke extracellular vesicles are released into the host’s internal environment. To understand extracellular vesicle biology further, isolation of the e...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2019-02-13 | PXD008737 | Pride
Extracellular vesicles Size exclusion chromatography and fasciola hepatica. Purification Differential centrifugation 
ProteomicsPROTEOMIC ANALYSIS OF EXTRACELLULAR VESICLES FROM FASCIOLA HEPATICA HATCHING EGGS AND JUVENILES IN CULTURE
The identification of extracellular vesicles (EVs) in Fasciola hepatica has provided a new way to understand parasite-host communication. Most of the studies on EVs have focused on the adult stage of F. hepatica, but recently, the presence of EVs from different developmental stages has been reported...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2022-08-12 | PXD033086 | Pride
Extracellular vesicles  fasciola hepatica juveniles  fasciola hepatica eggs  helminth proteomics 
ProteomicsGlycosylation of somatic extracts and secretome in the infective stage of the helminth Fasciola hepatica
Fasciola hepatica is a global helminth parasite of humans and their livestock. The invasive stage of the parasite, the newly excysted juvenile (NEJs), relies on glycosylated excretedsecreted (ES) products and surface/somatic molecules to interact with host cells and tissues and to evade the host's i...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2024-01-26 | PXD045488 | Pride
Glycoproteomics Orbitrap Parasites Glycosylation Lc-ms/ms 
UnknownProteomic Analysis of Extracellular Vesicles From Fasciola hepatica Hatching Eggs and Juveniles in Culture.
Not available
S-EPMC9203882 | biostudies-literature
UnknownExtracellular vesicles from the trematodes Fasciola hepatica and Dicrocoelium dendriticum trigger different responses in human THP-1 macrophages.
Not available
S-EPMC10114103 | biostudies-literature
UnknownThe importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogens.
Not available
S-EPMC6411213 | biostudies-literature
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