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ProteomicsC. acnes CNS catheter infection elicits modest early inflammatory changes but long term alterations in the CSF proteome
Shunt infections lead to grave neurologic morbidity for patients especially when there is a delay in diagnosis. C. acnes is the third most common cause of cerebrospinal fluid (CSF) shunt infection and is underdiagnosed due to the difficulty in culturing this fastidious, slow growing pathogen. Curren...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-15 | PXD020527 | Pride
Cytokine Inflammation Csf Proteome Biomarker C. acnes Shunt infection 
ProteomicsBacteria Commonly Associated with Central Nervous System Catheter Infections Elicit Distinct CSF Proteome Signatures
Cerebrospinal fluid (CSF) shunt infection is a common and devastating complication of the treatment of hydrocephalus. Timely and accurate diagnosis is essential as these infections can lead to long term neurologic consequences like seizures, decreased IQ and impaired school performance. Currently th...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-01-30 | PXD038238 | Pride
Inflammation P. aeruginosa Central nervous system infection Cns Csf Infection Shunt infection Proteome S. epidermidis Biomarker C. acnes 
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