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TranscriptomicsSkin Deep: Early Mucosal Responses in Blue Catfish (Ictalurus furcatus) Skin to Aeromonas hydrophila Infection
Fish skin is a critical regulatory organ, serving not only as a physical barrier to pathogen entry, but also as a sophisticated integrator of aquatic environmental, social and nutritional cues through roles in immunity, osmoregulation, and endocrine signaling. Integral to the complexity of teleost s...
ORGANISM(S): Ictalurus furcatus 
2014-06-17 | E-GEOD-42491 | biostudies-arrayexpress
ProteomicsMucosal Immunity of Puffer Fish against bacterial Infection
This study established immunological and particularly antibacterial proteins in the skin mucus of Obscure puffer against A. hydrophila infection. These proteins could be potential biomarkers to be studied for prevention of bacterial disease in fish. Overall, the study provides primary insights into ...
ORGANISM(S): Takifugu obscurus 
2024-08-16 | PXD054382 | Pride
Pufferfish Immune response Mass spectrometry Skin mucus Bacterial infection. 
TranscriptomicsExpression data from mouse oral keratinocyte
Keratinocytes are the major constituent of epithelial cells at mucosal surfaces and skin, which cover organs, internal cavities and the body. Traditionally, keratinocytes have been considered as an inert component of the multilayered epithelium to protect the subepithelial compartments from the path...
ORGANISM(S): Mus musculus 
2011-03-19 | E-GEOD-28035 | biostudies-arrayexpress
TranscriptomicsGenomic Fingerprints of DC Subsets in the Human Vaginal Mucosa, Skin, and Blood
Dendritic cells (DC) localize throughout the body, where they sense and capture invading pathogens to induce protective immune responses. Hence, harnessing the biology of tissue-resident DC is crucial for the rational design of vaccines against pathogens. Herein, we characterized the transcriptomes ...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-GEOD-54480 | biostudies-arrayexpress
ProteomicsEffects of Experimental Terrestrialization on the Skin Mucus Proteome of African Lungfish (Protopterus dolloi), part 1
Animal mucosal barriers constantly interact with the external environment and this interaction is markedly different in aquatic and terrestrial environments. Transitioning from water to land was a critical step in vertebrate evolution but the immune adaptations that mucosal barriers such as the skin...
ORGANISM(S): Protopterus dolloi 
2018-10-19 | PXD008981 | Pride
Mucosal immunity  mucus  proteomics  terrestrialization  african lungfish  skin  lc-ms/ms 
ProteomicsEffects of Experimental Terrestrialization on the Skin Mucus Proteome of African Lungfish (Protopterus dolloi), part 2
Animal mucosal barriers constantly interact with the external environment and this interaction is markedly different in aquatic and terrestrial environments. Transitioning from water to land was a critical step in vertebrate evolution but the immune adaptations that mucosal barriers such as the skin...
ORGANISM(S): Protopterus dolloi 
2018-10-19 | PXD008982 | Pride
Mucosal immunity  mucus  proteomics  terrestrialization  african lungfish  skin  lc-ms/ms 
TranscriptomicsHuman transcriptome pattern of primary cutaneous lesions from patients with localized cutaneous leishmaniasis and mucosal leishmaniasis
We evaluated the trancriptome of primary cutaneous leisions caused by infection with Leishmania braziliensis. mRNA-seq technique was used to study the trancriptome of both host and parasite. A total of 10 samples was obtained from primary skin ulcers of two extreme clinical forms of American tegumen...
ORGANISM(S): Homo sapiens 
2012-10-24 | E-GEOD-33601 | biostudies-arrayexpress
GenomicsSkin immune response of rainbow trout (Oncorhynchus mykiss) infected with infectious hematopoietic necrosis virus
Skin immune response of rainbow trout (Oncorhynchus mykiss) infected with infectious hematopoietic necrosis virus
PRJNA1059645 | ENA
TranscriptomicsGene expression profiles in dendritic cells from Peyer's patches and epidermal of skin
Many studies have shown that the mucous membranes and skin are at the interface with different external environments and face the disparity of pathogenic effects, such as biological agents, chemical or physical environment. This difference may demand distinct immune responses. However, the mechanism...
ORGANISM(S): Mus musculus 
2009-04-28 | E-GEOD-15754 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mucosal mast cell in vitro differentiation
The aim of the study was to find novel genes highly upregulated in mouse mucosal mast cells. To carry it out, differentiating progenitor cells were isolated on day4 of culturing and compared to mature mucosal mast cells obtained by day20. Experiment Overall Design: The experiment was carried out on ...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6192 | biostudies-arrayexpress
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