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ProteomicsHuman SKI component SKIV2L regulates telomeric DNA-RNA hybrids and prevents telomere fragility
Super killer (SKI) complex is a well-known cytoplasmic 3′ to 5′ mRNA decay complex that functions with the exosome to degrade excessive and aberrant mRNAs. Recently, SKIV2L, the 3′ to 5′ RNA helicase of the human SKI (hSKI) complex has been implicated with the extraction of mRNA at stalled ribosomes...
ORGANISM(S): Homo sapiens (Human) 
2024-10-03 | PXD046955 | Pride
Skiv2l Genome instability Dna-rna hybrids Dna damage Telomere 
GenomicsTotal RNA sequencing of Skiv2l-deficient mouse epidermis
Total RNA sequencing of Skiv2l-deficient mouse epidermis
PRJNA764583 | ENA
GenomicsRNA sequencing of pro-B from Skiv2l-deficient B cells
RNA sequencing of pro-B from Skiv2l-deficient B cells
PRJNA780333 | ENA
TranscriptomicsTotal RNA sequencing of Skiv2l-deficient mouse epidermis
To identify differentially epxressed RNAs in Skiv2l-deficient mouse epidermis
ORGANISM(S): Mus musculus 
2022-11-18 | GSE184418 | GEO
TranscriptomicsRNA sequencing of pro-B from Skiv2l-deficient B cells
To identify differentially expressed mRNAs in Skiv2l-deficient pro-B cells.
ORGANISM(S): Mus musculus 
2022-03-01 | GSE188795 | GEO
UnknownThe mammalian SKIV2L RNA exosome is essential for early B cell development.
Not available
S-EPMC9376044 | biostudies-literature
UnknownHuman SKI component SKIV2L regulates telomeric DNA-RNA hybrids and prevents telomere fragility.
Not available
S-EPMC11530851 | biostudies-literature
UnknownRNA helicase SKIV2L limits antiviral defense and autoinflammation elicited by the OAS-RNase L pathway.
Not available
S-EPMC11405415 | biostudies-literature
UnknownThe SKIV2L RNA exosome limits activation of the RIG-I-like receptors.
Not available
S-EPMC4139417 | biostudies-literature
UnknownCase Report: Novel Compound-Heterozygous Variants of SKIV2L Gene that Cause Trichohepatoenteric Syndrome 2.
Not available
S-EPMC8527088 | biostudies-literature
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