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TranscriptomicsComparisons of the global gene profile between C-CPE treated- and untreated- SKOV-3 ovarian cancer cells.
A microarray analysis was performed to compare the global gene expression profile between C-CPE treated- and untreated- SKOV-3 ovarian cancer cells. SKOV-3 cells were treated with or without C-CPE for 72 hours, and total RNA was extracted and microarray was perfomed to compare the gene profiling cha...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-22421 | biostudies-arrayexpress
TranscriptomicsOffect of ATP depletion on SKOV-3 cells using apyrase
The purpose of this experiment was to identify the effects of ATP depletion (using apyrase) on a metastatic ovarian carcinoma cell line (SKOV-3) and compare it to a non-treated sample. Cells were treated either with media alone or with media with apyrase during 24h. SKOV-3 cells were harvested durin...
ORGANISM(S): Homo sapiens 
2023-12-31 | E-MTAB-13598 | biostudies-arrayexpress
TranscriptomicsAffymetrix GeneChip® human gene 2.0 ST array analysis of SKOV-3 human ovarian cancer cells following siRNA knockdown of MAD2 or TLR4 compared to cells transfected with scrambled negative control siRNAs.
Both TLR4 and MAD2 are biomarkers associated with paclitaxel resistance in ovarian cancer. Therefore we performed microarray analysis following knockdown of each marker in SKOV-3 cells to gain greater insight into key downstream pathways that these biomarkers activate and also determine any potenti...
ORGANISM(S): Homo sapiens 
2020-12-06 | E-MTAB-8440 | biostudies-arrayexpress
ProteomicsInward outward signaling in ovarian cancer: morpho-proteomics/phosphoproteomics profiling upon hypoxia and shear stress characterizes the adaptive potential of OVCAR-3 and SKOV-3 cells
With the onset of resistance, ovarian cancer cells display almost unpredictable adaptive potential. This may derive from genetic ancestry of the tumor cells and can be additionally tailored by post translational protein modifications (PTMs). The latter are profoundly shaped by the physical and chemi...
ORGANISM(S): Homo sapiens (Human) 
2022-01-13 | PXD027466 | Pride
Hypoxia Vasculogenic mimicry Fluid shear stress Morpho-metabolic adaptation Ovarian cancer 
GenomicsExpression data of transfected SKOV-3 cells before and after cisplatin treatment
Expression data of transfected SKOV-3 cells before and after cisplatin treatment
PRJNA602609 | ENA
TranscriptomicsHuman SKOV-3 cells, Input DNA vs ChIP DNA
Identification of target genes of PITX2 homeodomain transcription factor in ovary using human ovarian adenocarcinoma cells, SKOV-3 to determine the transcriptional network of PITX2. Genotypic Technology designed Custom Human Promoter 244k ChIP-on-chip Array (AMADID-019469)
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-29649 | biostudies-arrayexpress
GenomicsRNAseq of the effect of selenite and coated selenium nanoparticles against spheroids of SKOV-3 and OVCAR-3 ovarian cancer cell lines
RNAseq of the effect of selenite and coated selenium nanoparticles against spheroids of SKOV-3 and OVCAR-3 ovarian cancer cell lines
PRJNA628608 | ENA
GenomicsHuman SKOV-3 cells, Input DNA vs ChIP DNA
Identification of target genes of PITX2 homeodomain transcription factor in ovary using human ovarian adenocarcinoma cells, SKOV-3 to determine the transcriptional network of PITX2.
ORGANISM(S): Homo sapiens 
2013-05-01 | GSE29649 | GEO
TranscriptomicsExpression data from SKOV3 cells treated with SAHA or vehicle control
We performed a microarray experiment to assess SAHA-induced changes in expression of genes of the homologous recombination DNA repair pathway SKOV-3 ovarian cancer cells were treated with 1µM SAHA or vehicle-control (0.01% DMSO) for 6 or 24 hours, harvested and processed for RNA isolation. Data fo...
ORGANISM(S): Homo sapiens 
2014-03-19 | E-GEOD-53603 | biostudies-arrayexpress
TranscriptomicsRole of HBO1 (KAT7/MYST2) in ovarian cancer cell line SKOV-3
Analysis of change in transcriptosome after HBO1 knockdown in SKOV-3 ovarian cancer cell line
ORGANISM(S): Homo sapiens 
2019-02-01 | GSE89921 | GEO
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