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ProteomicsHuman skull base chordoma LC-MSMS
The prognostic factors of skull base chordoma associated with outcomes of patients after surgical resection remain poorly defined. This project aimed to identify a novel prognostic factor for patients with skull base chordoma. Using a proteomics approach, we screened tumor biomarkersthat upregulated...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025894 | Pride
Human Lc-msms Skull base chordoma 
ProteomicsProteogenomic Characterization of Skull-base Chordoma
Skull-base chordoma (SBC) is a rare, aggressive bone cancer with a high recurrent rate. Genomic studies of SBC have improved our understanding of the disease’s biology. However, the molecular biological characteristics and the effective therapy of SBC remain unknown. Here, we carried out an integrat...
ORGANISM(S): Homo Sapiens 
PXD053550 |
TranscriptomicsA novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-kB signaling in chordoma biology [SNP array]
Chordoma is a rare primary bone malignancy that arises in the skull base, spine and sacrum and originates from remnants of the notochord. These tumors are typically resistant to conventional chemotherapy, and to date there are no FDA-approved agents to treat chordoma. The lack of in vivo models of c...
ORGANISM(S): Homo sapiens 
2013-12-22 | E-GEOD-50136 | biostudies-arrayexpress
UnknownWRN Cys1367Arg polymorphism is not associated with skull base chordoma.
Not available
S-EPMC4051466 | biostudies-literature
GenomicsMethylation Based Reclassification and Risk Stratification of Skull Base Chordoma
Methylation Based Reclassification and Risk Stratification of Skull Base Chordoma
PRJNA844394 | ENA
UnknownThe brachyury Gly177Asp SNP is not associated with a risk of skull base chordoma in the Chinese population.
Not available
S-EPMC3856003 | biostudies-literature
UnknownProteogenomic characterization of skull-base chordoma.
Not available
S-EPMC11436687 | biostudies-literature
UnknownGenomic and transcriptomic characterization of skull base chordoma.
Not available
S-EPMC5352057 | biostudies-literature
GenomicsHomo sapiens
Whole genome sequencing of skull-base chordoma
PRJNA679996 | ENA
Methylation profilingMethylation Based Reclassification and Risk Stratification of Skull Base Chordoma
Epigenome analysis of skull base chordoams Genome wide DNA methylation profiling of 46 skull base chordomas. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in skull base chorodma samples. Samples included 46 sku...
ORGANISM(S): Homo sapiens 
2022-06-02 | GSE205331 | GEO
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