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TranscriptomicsTranscription profiling of human NIH 3T3 inducible cell line to study the role of PKR in regulating gene expression
PKR is an interferon induced serine/threonine protein kinase, that is activated by double stranded RNA. PKR plays an important role in the antiviral defense by interferon. In addition to its role in translation, PKR participates in several signaling pathways to transcription. The goal of this experi...
ORGANISM(S): Mus musculus 
2004-01-30 | E-MEXP-50 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse model of asthma reveals the effects of resiquimod treatment on the asthma transcriptome
Resiquimod is a nucleoside analog belonging to the imidazoquinoline family of compounds which is known to signal through Toll-like receptor 7. Resiquimod treatment has been demonstrated to inhibit the development of allergen induced asthma in experimental models. Despite this demonstrated effectiv...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-13032 | biostudies-arrayexpress
TranscriptomicsExpression Data from HNF4a RNAi Knockdown in HepG2 cells
HNF4a is an important liver transcription factor that regulates at least a thousand genes in the liver. Here we used expression profiling in HepG2 cells, a hepatocellular carcinoma cell line, in which HNF4a was knocked down by RNAi to identify some of those target genes. This dataset accompanies the...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-29084 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse NIH3T3 cells over-expressing RNA-dependent serine/threonine protein kinase (PKR)PKR
Global analysis of gene expression in NIH3T3 cells over-expressing RNA-dependent serine/threonine protein kinase (PKR).
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-682 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Early Myogenesis - Affymetrix Dataset
Analysis of Early Myogenesis Reveals an Extensive Set of Transcriptional Regulators Whose Knock-down Can Inhibit Differentiation Myogenesis is a tightly controlled process involving the transcriptional activation and repression of thousands of genes. Although many components of the transcriptional n...
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-16992 | biostudies-arrayexpress
UnknownLong-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.
Not available
S-EPMC2818943 | biostudies-literature
UnknownSharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals.
Not available
S-EPMC11105950 | biostudies-literature
TranscriptomicsMapping Clinical and Expression QTL in a Sex-Dependent Effect of Host Susceptibility to Influenza H3N2/HK/1/68-MA20
Seasonal influenza outbreaks and recurrent influenza pandemics present major challenges to public health. By studying immunological responses to influenza in different host species, it may be possible to discover common mechanisms of susceptibility in response to various influenza strains. This coul...
ORGANISM(S): Mus musculus 
2012-05-01 | E-GEOD-35888 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse T3-L1 preadipocytes treated with the steroid hormone dexamethasone in biological and technical replicates to illustrate validation methods
DNA microarrays are popular tools for measuring gene expression of biological samples. This ever increasing popularity is ensuring that a large number of microarray studies are conducted, many of which with data publicly available for mining by other investigators. Under most circumstances, validati...
ORGANISM(S): Mus musculus 
2006-07-28 | E-MEXP-774 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Early Myogenesis - Illumina Dataset
Myogenesis is a tightly controlled process involving the transcriptional activation and repression of thousands of genes. Although many components of the transcriptional network are known for the later phases of myogenesis, relatively little work has described the transcriptional landscape within th...
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-17038 | biostudies-arrayexpress
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