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Transcriptomic analysis of SLAN+ vs SLAN- non-classical monocytes
The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [scRNA-seq]
Monocytes can be classified into four different subsets: classic, intermediate and SLAN- and SLAN+ non-classical monocytes. SLAN+ monocytes are significantly reduced in MM patients compare to the frequency found in healthy adults (HA). Thus, we sought to analyze the transcriptome of SLAN- and SLAN+ ...
ORGANISM(S): Homo sapiens 
2023-11-05 | GSE122171 | GEO
The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [Bulk RNA-seq]
Peripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16. A major fraction of the NC-monocytes has been shown to express the 6-sulfo Lac...
ORGANISM(S): Homo sapiens 
2023-10-19 | GSE241266 | GEO
Peripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16. A major fraction of the NC-monocytes has been shown to express the 6-sulfo Lac...
ORGANISM(S): Homo sapiens 
2023-10-19 | GSE242301 | GEO
Deciphering the fate of slan+-monocytes in tonsils by gene expression profiling
Abstract: Human 6-sulfo LacNac (slan)+ cells have been subject to a paradigm debate. They have previously been classified as a distinct dendritic cell (DC) subset. However, evidence has emerged that they may be more related to monocytes than to DC. To gain deeper insight into the functional speciali...
ORGANISM(S): Homo sapiens 
2018-08-24 | GSE98694 | GEO
slan+-monocytes represent a subset of the “non-classical” CD14dim/-CD16++ monocytes, which are characterized by the expression of the so-called “slan” antigen, recognized by specific monoclonal antibodies. slan+-cells can be identified in peripheral tissues including tonsils. However, their origin f...
ORGANISM(S): Homo sapiens 
2021-11-19 | GSE136107 | GEO
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