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UnknownSlipped-strand DNAs formed by long (CAG)*(CTG) repeats: slipped-out repeats and slip-out junctions.
Not available
S-EPMC137136 | biostudies-literature
UnknownDetection of slipped-DNAs at the trinucleotide repeats of the myotonic dystrophy type I disease locus in patient tissues.
Not available
S-EPMC3868534 | biostudies-literature
ProteomicsAntagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Ongoing CAG expansions in Spinocerebellar ataxia type 1 (SCA1) and Huntington disease (HD) brains exacerbate disease.  Expansions involve aberrant repair of mutagenic slipped-DNAs, formed from single-stranded DNAs.  Whether singlestranded DNA-binding proteins prevent or facilitate expansions is unkn...
ORGANISM(S): Homo sapiens (Human) 
2023-10-13 | PXD044158 | Pride
Cag repeat expansion diseases  spinocerebellar ataxia type 1 (sca1)  huntington's disease (hd)  somatic cag repeat expansions  rpa (single-strand dna binding protein  alternative-rpa (alt-rpa)  dna repair Slipped-dnas  post-mortem brains Sca1 mice 
UnknownAbsence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks.
Not available
S-EPMC5096786 | biostudies-literature
UnknownAntagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Not available
S-EPMC11209935 | biostudies-literature
UnknownCTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repair.
Not available
S-EPMC2785351 | biostudies-literature
UnknownProcessing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.
Not available
S-EPMC4176329 | biostudies-literature
UnknownRevisiting mutagenesis at non-B DNA motifs in the human genome.
Not available
S-EPMC10225297 | biostudies-literature
UnknownA minimal i-motif stabilized by minor groove G:T:G:T tetrads.
Not available
S-EPMC3526289 | biostudies-literature
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