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UnknownDose-limiting toxicity after hypofractionated dose-escalated radiotherapy in non-small-cell lung cancer.
Not available
S-EPMC3837093 | biostudies-literature
UnknownSmall Cationic Cysteine-Rich Defensin-Derived Antifungal Peptide Controls White Mold in Soybean.
Not available
S-EPMC10532163 | biostudies-literature
TranscriptomicsA novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples
Growing evidence suggests that DNA methylation plays a role in tissue-specific differentiation. Current approaches to methylome analysis using MBD-enrichment are restricted to large (M-bM-^IM-%1 M-BM-5g) DNA samples, limiting the analysis of small tissue samples. Here we present a technique which en...
ORGANISM(S): Mus musculus 
2013-06-10 | E-GEOD-46683 | biostudies-arrayexpress
MetabolomicsElevated brain manganese induces motor disease by upregulating the kynurenine pathway of tryptophan metabolism
Elevated brain levels of the essential metals manganese (Mn), copper, or iron induce motor disease. However, mechanisms of metal-induced motor disease are unclear and treatments are lacking. Elucidating the mechanisms of Mn-induced motor disease is particularly important because occupational and env...
2025-03-31 | MTBLS975 | MetaboLights
UnknownChickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action.
Not available
S-EPMC11637438 | biostudies-literature
ProteomicsHuman pancreatic cancer LC-MSMS
Despite decades of effort, pancreatic adenocarcinoma (PDAC) remains an intractable clinical challenge. An insufficient understanding of mechanisms underlying tumor cell responses to chemotherapy contributes significantly to the lack of effective treatment regimens. Here, paclitaxel, a first-line che...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082878 | MassIVE
TranscriptomicsComparison between NuGEN's WT-Ovation Pico and One-Direct Amplification Systems
Differential gene expression between groups of homogenous cell types is a biological question whose time has come. RNA can be extracted from small numbers of cells, such as those isolated by laser capture microdissection, but the small amounts obtained often require amplification to enable whole ge...
ORGANISM(S): Arabidopsis thaliana 
2010-06-08 | E-GEOD-21981 | biostudies-arrayexpress
TranscriptomicsDifferentiation mutants in the protozoan parasite Toxoplasma gondii.
Two forms of the protozoan parasite Toxoplasma gondii are associated with intermediate hosts such as humans: rapidly growing tachyzoites are responsible for acute illness, whereas slowly dividing encysted bradyzoites can remain latent within the tissues for the life of the host. In order to identify...
ORGANISM(S): Toxoplasma gondii 
2005-08-13 | E-GEOD-3119 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of murine livers after resveratrol treatment of mice on a high-calorie diet
Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including yeast, worms, and flies. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction (CR). Here we show that resveratr...
ORGANISM(S): Mus musculus 
2008-06-21 | E-GEOD-6089 | biostudies-arrayexpress
TranscriptomicsGene expression of distinct lung dendritic cell subsets
Pulmonary dendritic cells are heterogenous cells comprise four distinct subsets including two conventional dendritic cell subsets, CD103+ and CD11bhiCD14lo cells, and two monocyte-derived dendritic cell subsets. Their functions in terms of migration and T cell activation are distinct, but genes regu...
ORGANISM(S): Mus musculus 
2015-04-02 | E-GEOD-64896 | biostudies-arrayexpress
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