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TranscriptomicsEndogenous shRNAs, siRNAs, and Other Microprocessor-independent, Dicer-dependent Small RNAs in Mouse ES Cells
Canonical microRNAs (miRNAs) require two processing steps: the first by the Microprocessor, a complex of DGCR8 and Drosha, and the second by Dicer. dgcr8delta/delta mouse embryonic stem cells (mESCs) have less severe phenotypes than dicer1delta/delta mESCs, suggesting a physiological role for Microp...
ORGANISM(S): Mus musculus 
2008-09-09 | E-GEOD-12521 | biostudies-arrayexpress
GenomicsMuTHER adipose tissue small RNA expression
We investigate the naturally occurring variation of small RNA expression in conjunction with genetic and gene expression variation. We shall assess the variation in subabdominal fat tissue small RNA levels in 168 unrelated MuTHER individuals. Using gene expression data from the same samples, we can ...
EGAS00001000212 | EGA
TranscriptomicsSmall RNAs serve as a genetic buffer against genomic shock in Arabidopsis interspecific hybrids and allopolyploids
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are produced in diverse species and control gene expression and epigenetic regulation. Although physiological and developmental roles of miRNAs and siRNAs have been extensively studied in plants and animals, expression diversity and evolution of...
ORGANISM(S): Arabidopsis arenosa 
2009-07-30 | E-GEOD-15443 | biostudies-arrayexpress
GenomicsChIP-seq of Arabidopsis ARGONAUTE-small RNA interactions in Arabidopsis thaliana identified by high-throughput sequencing
The goal of this study was to identify small RNA-ARGONAUTE interactions in Arabidopsis. Co-immunoprecipitation assays followed by high-throughput sequencing were done to identify small RNA associated with HA-AGO2 and HA-AGO7. Experiment Overall Design: Sequencing-by-synthesis technology was used to ...
ORGANISM(S): Arabidopsis thaliana 
2009-08-30 | E-GEOD-12037 | biostudies-arrayexpress
TranscriptomicsPhytophthora have distinct endogenous small RNA populations that include short interfering and microRNAs: Phytophthora infestans small RNA
Deep sequencing of small RNAs from three Phytophthora species, P. infestans, P. ramorum and P. sojae, was done to systematically analyze small RNA-generating components of Phytophthora genomes. We found that each species produces two distinct small RNA populations that are predominantly 21- or 25-nu...
ORGANISM(S): Phytophthora infestans 
2013-10-21 | E-GEOD-50030 | biostudies-arrayexpress
UnknownPriorities for research in miscarriage: a priority setting partnership between people affected by miscarriage and professionals following the James Lind Alliance methodology.
Not available
S-EPMC5629698 | biostudies-literature
UnknownDialectical behavior therapy for justice-involved veterans: Changes in treatment targets in a small, pre-post design clinical trial.
Not available
S-EPMC10570393 | biostudies-literature
GenomicsGenentech Small Cell Lung Cancer (SCLC) Screen
Exome capture, RNA-Seq, whole genome sequencing of set of Small Cell Lung Cancer samples.
EGAS00001000334 | EGA
TranscriptomicsMutant analysis of C. elegans small RNAs, 5p-end-independent
These datasets profile the expression of small RNAs with 3p hydroxyls (including endo-siRNAs, miRNAs, and 21U-RNAs) in young adult worms from the wt and prg-1 mutant backgrounds. They were prepared using an approach that captures small RNAs independent of the covalent status of their 5p termini, as...
ORGANISM(S): Caenorhabditis elegans 
2008-06-15 | E-GEOD-11736 | biostudies-arrayexpress
GenomicsEGAS00001000212-sc-20120201 - samples
MuTHER adipose tissue small RNA expression
EGAD00001000105 | EGA
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