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TranscriptomicsPromoter directionality is controlled by U1 snRNP and polyadenylation signals
Transcription of the mammalian genome is pervasive, but productive transcription outside of protein-coding genes is limited by unknown mechanisms. In particular, although RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive elongation occurs primarily in the s...
ORGANISM(S): Mus musculus 
2013-06-28 | E-GEOD-46433 | biostudies-arrayexpress
UnknownSm core variation in spliceosomal small nuclear ribonucleoproteins from Trypanosoma brucei.
Not available
S-EPMC1589986 | biostudies-literature
ProteomicsProteins that interact with PHAX and UAP56 from HeLa nuclear extracts
HeLa nuclear extracts and RNase A were incubated with GST-PHAX and FLAG-UAP56 in the presence of ATP. The mixture was subjected to immunoprecipitation. The bound proteins were eluted with FLAG peptide. The eluate was subjected to GST pull-down. The bound proteins were treated with HRV 3C protease. S...
ORGANISM(S): Homo Sapiens (human) 
2025-06-28 | PXD053480 | JPOST Repository
UnknownU bodies are cytoplasmic structures that contain uridine-rich small nuclear ribonucleoproteins and associate with P bodies.
Not available
S-EPMC1899408 | biostudies-literature
UnknownSumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis.
Not available
S-EPMC423232 | biostudies-literature
UnknownHeterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer.
Not available
S-EPMC4941349 | biostudies-literature
GenomicsNopp140-chaperoned 2’-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity
Nopp140-chaperoned 2’-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity
PRJNA724033 | ENA
TranscriptomicsNopp140-chaperoned 2’-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity
Spliceosomal small nuclear RNAs (snRNAs) are modified by small Cajal body (CB) specific ribonucleoproteins (scaRNPs) to ensure snRNP biogenesis and pre-mRNA splicing. However, the function and subcellular site of snRNA modification are largely unknown. We show that CB localization of the protein Nop...
ORGANISM(S): Homo sapiens 
2021-07-01 | GSE173171 | GEO
UnknownActivation of alpha-tropomyosin exon 2 is regulated by the SR protein 9G8 and heterogeneous nuclear ribonucleoproteins H and F.
Not available
S-EPMC1636816 | biostudies-literature
UnknownCore structure of the U6 small nuclear ribonucleoprotein at 1.7-A resolution.
Not available
S-EPMC4141773 | biostudies-literature
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